Inflammatory Responses and Immunity under Stress
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 2192
Special Issue Editor
Special Issue Information
Dear Colleagues,
Activation of stress response systems such as the autonomic nervous system (ANS) and hypothalamic–pituitary–adrenal (HPA) axis is imperative for survival and adaptation. Since Hans Selye published his first manuscript on the general adaptation syndrome, stress research has provided insights into how the ANS and HPA axis interact and modulate key immune functions, yet much remains to be discovered. Chronic exposure to stressors together with unhealthy lifestyle factors, such as a lack of good-quality sleep, reduces coping capacity. The resulting chronic allostatic load and activation of stress response systems can greatly affect immunity towards all types of pathogens and may lead to immune dysfunction, hypersensitivity or autoimmune disease.
In this Special Issue, we welcome research articles as well as reviews covering recent advances in stress-modulated innate and adaptive immune functions, molecular and cellular mechanisms as well as integrative physiology and stress biomarker research. We also encourage contributions from research on extreme environments/earth-bound space flight analogues employing stressors such as isolation and confinement.
Dr. Judith-Irina Buchheim
Guest Editor
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Keywords
- psychoneuroimmunology
- immunity
- stress-modulated immune response
- autoimmunity
- hypersensitivity
- stressors
- environmental stress
- allostatic load
- autonomic nervous system (ANS)
- hypothalamic–pituitary–adrenal (HPA) axis
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