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Special Issue "Advances in the Research of Neural Circuits"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 30 June 2022.

Special Issue Editor

Prof. Dr. Masahito Yamagata
E-Mail Website
Guest Editor
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
Interests: neural circuit formation; synapse formation; adhesion molecule; extracellular matrix; connectomics; synthetic biology; genome editing; cell atlas; visual system in birds and mice
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The neuron is a fundamental component of brain function. However, neurons do not function individually—rather, they function through synaptically connected neural circuits and their networks, more recently known as the connectome. Unraveling the structure and function of neural circuits and connectomes requires the combination of various approaches, including biology, chemistry, physics, mathematics, engineering, information technology, clinical medicine, and psychology. In particular, there is no doubt that a panoply of molecular studies and tools have been at the center of this research. For example, biochemical, immunohistochemical, pharmacological, physiological, and genetical studies of synaptic molecules have revealed the roles of those components in the operation of distinct neural circuits as well as their unexpected anatomy and functions. In addition, new tools for connectomics such as traceable molecular reporters, caged compounds, recombinant viruses, calcium indicators, and optogenetics have opened new avenues to examine diverse neural circuits. These technical breakthroughs have helped to understand the neural development and the brain pathology of human aging.

This Special Issue welcomes original and review articles that demonstrate or summarize recent progress in the studies of any neural circuits, with a particular focus on molecular workforces and tools such as proteins, glycoconjugates, neurotransmitters, and lipids.

Prof. Dr. Masahito Yamagata
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • synapse
  • connectome
  • synaptic vesicle
  • synaptic cleft
  • postsynaptic density
  • axon
  • dendrite
  • aging
  • plasticity
  • neuropharmacology

Published Papers

This special issue is now open for submission.
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