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Cellular and Molecular Mechanisms in Diabetes Therapies

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 6

Special Issue Editor


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Guest Editor
Biosanitary Research Institute (IIB-VIU), Valencian International University (VIU), 46002 Valencia, Spain
Interests: diabetes and diabetes complication; cardiovascular; peripheral artery disease (PAD); critical limb ischemia pathology (CLI); regulatory standards; clinical trials; advanced therapies; advanced therapies medicinal products (ATMP); stem cells; good manufacturing practice (GMP); quality assurance (QA); quality control (QC); molecular and cellular biology; epigenetics; microRNAs
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Special Issue Information

Dear Colleagues,

Diabetes mellitus is a major and growing global health concern, characterized by complex metabolic dysfunctions and a wide spectrum of complications. Despite notable progress in therapeutic development, a deeper understanding of the cellular and molecular pathways that govern diabetes pathogenesis and treatment responses is urgently needed to improve clinical outcomes.

This Special Issue of the International Journal of Molecular Sciences, under the section Molecular Endocrinology and Metabolism, aims to showcase recent advances in the elucidation of molecular and cellular mechanisms involved in diabetes and its therapies. We welcome original research articles, reviews, and short communications focusing on topics ranging from β-cell dysfunction and insulin signaling to immune regulation, metabolic crosstalk, and innovative therapeutic approaches such as gene and stem cell therapies.

Particular emphasis will be placed on studies that integrate molecular insights with translational potential, as well as those that explore novel diagnostic or therapeutic targets.

Dr. Abdelkrim Hmadcha
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diabetes
  • β-cells
  • insulin signaling
  • inflammation
  • metabolic pathways
  • molecular mechanisms
  • stem cell therapy
  • gene therapy
  • oxidative stress
  • microbiota
  • immune modulation
  • epigenetics
  • regenerative medicine
  • therapeutic targets

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Published Papers

This special issue is now open for submission.
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