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The Role of Phytochemicals in Cancer Treatment and Prevention

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 20 October 2024 | Viewed by 136

Special Issue Editors

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Guest Editor
Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Bialystok, ul. Mickiewicza 2a, 15-230 Bialystok, Poland
Interests: phytochemistry; chromatography; spectral methods; polyphenols

Special Issue Information

Dear Colleagues,

Phytochemicals, which are compounds found in plants, have gained significant recognition in the field of cancer treatment and its prevention, due to their potential health benefits. While they are not considered essential nutrients like vitamins and minerals, phytochemicals have been shown to possess antioxidant, anti-inflammatory, and anticancer properties. They play different roles like cellular signaling and immune system modulations, angiogenesis inhibition, detoxification support, or epigenetic modifications as well as antioxidant and anti-inflammatory roles, which come from their properties. While phytochemicals show potential in cancer prevention and treatment, it is important to note that they are not a substitute for conventional cancer therapies. Although research on natural compounds and cancer is promising, it is essential to keep in mind that many studies have been conducted in cell cultures or animal models, but more examinations are needed to fully understand their efficiency and safety in humans. However, incorporating a variety of phytochemical-rich foods into a balanced diet may contribute to overall health and reduce the risk of cancer development. A crucial fact is that natural compounds should not be used as a replacement for any traditional treatments but rather only as complementary methods to support overall health and well-being. The aim of our Special Issue is to collect original research and review manuscripts on biological or pharmacological approaches to target the mechanism of action and metabolism for cancer prevention and therapy.

This project was led by Dr. Michał Tomczyk, Dr. Jakub Strawa and Dr. Katarzyna Jakimiuk (Medical University of Bialystok, Poland).

Dr. Michał Tomczyk
Dr. Jakub Strawa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cancer
  • cell culture
  • isolation and structure elucidation
  • metabolism
  • molecular mechanism
  • natural product chemistry
  • phytochemicals
  • secondary metabolites
  • structure–activity relationships
  • targeted therapy

Published Papers

This special issue is now open for submission.
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