From Kidney Disease to Hypertension: Molecular Basis and Pathophysiology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 July 2025 | Viewed by 1732
Special Issue Editor
Interests: renal system; renal injury; arterial hypertension; renal dysfunction; renin–angiotensin system
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The intricate relationship between kidney disease and hypertension underscores a significant area of research, as kidney dysfunction often leads to or exacerbates high blood pressure. The molecular mechanisms underlying this connection involve interactions within the renin-angiotensin-aldosterone system (RAAS), endothelial cell dysfunction, systemic inflammation, and other complex mechanisms. Recent studies have shed light on how these pathways contribute to the development and progression of both conditions, revealing potential new targets for therapeutic intervention.
This special issue aims to delve into the intricate mechanisms that underlie the complex relationship between kidney disease and hypertension. Whether it's deciphering novel cellular and molecular mechanisms, elucidating regulatory networks, or examining genes that contribute to the advancement of hypertension associated with renal pathologies, we invite researchers from diverse fields to share their groundbreaking insights and contributions to this special issue. We aim to offer novel insights into the pathophysiological processes involved in kidney-related hypertension, thereby illuminating potential avenues for the development of innovative treatment strategies.
Dr. Alexis A. Gonzalez
Guest Editor
Manuscript Submission Information
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Keywords
- renin-angiotensin-aldosterone system
- endothelial cell dysfunction
- systemic inflammation
- hypertension
- oxidative stress
- vascular remodeling
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