High-Throughput Molecular Function Screens
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (31 January 2021) | Viewed by 9468
Special Issue Editors
2. School of Life Sciences, University of Nevada Las Vegas, Las Vegas, NV 89154-4004, USA
Interests: bioinformatics; virology; personalized medicine; functional genomics; minimotifs; HIV; NHEJ; gene editing; high-throughput screening
Special Issues, Collections and Topics in MDPI journals
Interests: virology; functional genomics; HIV; NHEJ; gene editing; high-throughput screening; Infection biology
Interests: functional proteomics; phagocytosis; retinal cell biology; retinal degenerative diseases; alzheimer’s disease; obesity; molecular and cell biology; phage display
Special Issue Information
Dear Colleagues,
High-throughput screening (HTS) technologies have transformed the rate of research within the biomedical sciences. While some of these technologies identify nucleic acid sequences, gene expression profiles, metabolites, or candidate drugs, many are now focused on different molecular functions. Technologies that define molecular functional relationships have the potential to systematize our understanding of the mechanistic basis driving cell process and their vulnerabilities that manifest as disease. In this Special Issue, the collection of review articles covers both the state-of-the-art functional high throughput screening technologies, and the future prospects for impacting biomedical sciences.
This volume will represent a comprehensive collection of information related to this growing field. I hope that you are willing to prepare a comprehensive review related to an area related in High-throughput Molecular Function Screens that has not yet been covered in this Special Issue. The topics we intend to cover do not merely identify a class or the nature of molecules like metabolomics or transcriptomics, but rather identify functional connection between biomolecules. Topics we intend to cover are functional proteomics (phage display, yeast 2- hybrid, peptide arrays, affinity MS/MS), functional genomics (RNAi, shRNA, and CRISPR/Cas screening, CHIP-Seq, massively parallel functional genomic screens, functional NGS, microarrays or RNA-Seq as applied to assaying transcription factors), high throughput affinity capture/enzymatic binding or activity based screens, as well as the algorithms and analytical tools required to mine high throughput screening data.
It would be greatly appreciated if you would contact Ronald Babu, one of the guest editors, indicating whether you agree to cover one of these or a related topic by proposing a title and abstract. If you cannot write a review for this issue, please feel free to suggest someone with the appropriate expertise.
We are looking forward to your favorable reply.
Prof. Dr. Martin R. Schiller
Dr. Ronald Benjamin Babu
Prof. Nora B. Caberoy
Guest Editors
Manuscript Submission Information
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Keywords
- High throughput functional screens
- Functional genomics
- Functional screening
- Assay development
- High Content Screening
- Algorithms and Analytical methods
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