Neuronal Differentiation and Neurodegeneration
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 118
Special Issue Editor
Interests: neurodegeneration; autophagy; neuronal differentiation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Differentiated and undifferentiated neuronal cells exhibit distinct morphological and functional features, which may account for their differential viability. Accordingly, environmental challenges may exert toxic effects depending not only on the duration or dose of exposure but also on the differentiation state of the cell. In addition, genetic factors can impair neuronal development, leading to altered neuronal structure and function, which may ultimately progress in neurodegenerative disorders.
The present Special Issue, “Neuronal Differentiation and Neurodegeneration”, aims to collect research studies investigating how neuronal survival is affected by various stimuli acting at genetic, molecular, and/or morphological levels when applied at different stages of neuronal differentiation. Original research articles based on diverse methodological approaches are welcome, as well as comprehensive reviews that provide a thorough and up-to-date overview of the state of the art in this rapidly advancing field.
Understanding how neuronal vulnerability evolves throughout the differentiation process may help identify novel neuroprotective strategies for pathologies involving either undifferentiated or differentiated neurons, such as neurodevelopmental disorders, brain tumors, and neurodegenerative diseases.
Dr. Michela Ferrucci
Guest Editor
Manuscript Submission Information
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Keywords
- neuronal development
- neurotoxicity
- neuroprotection
- neuronal survival
- neuronal morphology
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