Pediatric Central Nervous System Tumors: Mechanisms and Therapies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 28 February 2027 | Viewed by 467
Editors
Interests: pediatric brain tumors; patient-derived orthotopic xenograft models; recurrent tumor; invasion; drug testing
Special Issues, Collections and Topics in MDPI journals
2. Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, CO, USA
Interests: pediatric brain tumors; clinical trials; target therapy; drug response and therapy resistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Brain tumors remain the number one cause of cancer-related death in children. Even among survivors, many are left with long-term neurological deficiencies. Despite advances in genetic and epigenetic analysis and successful molecular subtyping over the past decade, our understanding of pediatric tumor biology is still incomplete. More importantly, many drugs and therapies have failed in clinical trials and our advances in overcoming the long-standing barriers of therapy have yet to lead to revolutionary breakthrough. While the need remains urgent for better understanding of tumor biology and for new and more effective therapies, pediatric brain cancers as a group are rare tumors, and study results are frequently scattered in different journals.
The aim of this Special Issue is to act as a platform that supports the rapid publication of new findings and to assemble a collection of relevant studies, in order to facilitate efficient communications and the broad distribution of this type of literature.
We are pleased to invite you to submit reports on tumorigenesis, genetic and epigenetic abnormalities, the development of targeted therapy, the identification of diagnostic markers, and the mechanistic examination of therapy responsiveness and resistance. Original research articles and reviews are both welcome.
We look forward to receiving your contributions.
Prof. Dr. Xiao-Nan Li
Dr. Holly Lindsay
Guest Editors
Manuscript Submission Information
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Keywords
- pediatric brain tumors
- genetics
- epigenetics
- therapy resistance
- invasion
- metastasis
- cell proliferation
- in vitro model
- animal model
- diagnostic marker
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