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Antimicrobial Agents for Wound Healing

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 20 May 2025 | Viewed by 1288

Special Issue Editors


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Guest Editor
Future Industries Institute, University of South Australia, Mawson Lakes, SA 5095, Australia
Interests: development of antibacterial nanomaterials; treatment of wound infection; preparation of smart hydrogels; targeted drug delivery; nanoparticle synthesis and applications
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Future Industries Institute, University of South Australia, Mawson Lakes SA 5095, Australia
Interests: wound healing; skin blistering; cancer; wound infection; fibrosis; inflammation; psoriasis; epidermolysis bullosa
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleague,

Effective wound healing remains a critical clinical challenge, particularly when open lesions evolve into chronic, non-healing wounds susceptible to infection that is difficult to treat due to the global threat of antibiotic resistance. This Special Issue seeks contributions focusing on the synthesis, development, and testing of novel antimicrobial agents and advanced materials that address complex wound environments to promote healing and regulate infections. By embracing a multidisciplinary approach, this Special Issue aims to bridge fields such as materials science, microbiology, bioengineering, and clinical research to propel new solutions in wound healing.

This Special Issue will provide a platform for cutting-edge research into the development and application of antimicrobial agents, biomaterials, and delivery systems with the potential to enhance wound healing outcomes. We invite manuscripts that address the following topics:

  1. Synthesis and Characterization of Antimicrobial Agents.

Innovative strategies in designing and characterizing novel antimicrobial compounds, including nanoparticles, peptides, and other bioactive agents, targeting drug-resistant bacteria commonly found in chronic wound infections.

  1. Development of Advanced Materials.

 Breakthrough biomaterials, such as hydrogels, polymeric scaffolds, dressings, and smart materials, that facilitate controlled antimicrobial release and support tissue regeneration in the wound environment.

  1. Multifunctional Dressings for Enhanced Healing.

 Research on multifunctional wound dressings that not only deliver antimicrobials but also promote tissue repair, by regulating the wound microenvironment. 

  1. Testing and Validation of Wound Healing Materials.

Preclinical and clinical studies evaluating the efficacy, safety, and biocompatibility of new materials through in vitro, ex vivo, and in vivo testing, with a focus on antimicrobial properties and wound healing effects.

  1. Interdisciplinary Wound Healing.

 Collaborative research bridging fields such as materials science, pharmacology, microbiology, and clinical practice to develop new approaches for effective wound healing strategies.

This Special Issue welcomes original research articles, reviews, and short communications that contribute to the development of novel approaches in antimicrobial agents and materials for wound healing. Experimental works dealing especially with clinical isolates responsible for worrying human infections will be particularly appreciated. We encourage submissions from multidisciplinary teams working to pioneer advanced solutions to chronic and infected wounds. It is our pleasure to invite you to submit your work to this Special Issue.

Dr. Hanif Haidari
Dr. Zlatko Kopecki
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial agents
  • multifunctional hydrogels
  • wound healing
  • chronic wounds
  • biomaterials
  • wound dressings
  • nano-antibiotics
  • nanomaterials
  • tissue regeneration
  • tissue engineering

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Published Papers (1 paper)

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Review

25 pages, 2209 KiB  
Review
Black Phosphorus Nanoflakes: An Emerging Nanomaterial for Clinical Wound Management and Biomedical Applications
by Luke S. Smith, Hanif Haidari, Anteneh Amsalu, Gordon S. Howarth, Saffron J. Bryant, Sumeet Walia, Aaron Elbourne and Zlatko Kopecki
Int. J. Mol. Sci. 2024, 25(23), 12824; https://doi.org/10.3390/ijms252312824 - 28 Nov 2024
Cited by 3 | Viewed by 1026
Abstract
Black phosphorus (BP), a two-dimensional material, has gathered significant attention over the last decade, primarily due to its unique physiochemical properties and potential role in various biomedical applications. This review provides an in-depth overview of the synthesis, nanomaterial properties, interactions, and biomedical uses [...] Read more.
Black phosphorus (BP), a two-dimensional material, has gathered significant attention over the last decade, primarily due to its unique physiochemical properties and potential role in various biomedical applications. This review provides an in-depth overview of the synthesis, nanomaterial properties, interactions, and biomedical uses of BP, with a particular focus on wound management. The structure, synthesis methods, and stability of BP are discussed, highlighting the high degree of nanomaterial biocompatibility and cytotoxicity. The antimicrobial properties of BP, including mechanisms of action and preclinical studies to date, are examined, emphasizing the effectiveness of BP against various clinical pathogens relevant to wound management. Additionally, the versatility of BP in biomedical implementations is highlighted through utilization in drug delivery, imaging, and photothermal therapy, with a focus on scalability and reproducibility with outlined future perspectives. Despite identified challenges for translation in clinical uses, BP nanomaterial has significant potential as a versatile platform in biomedical applications, especially in wound management. Full article
(This article belongs to the Special Issue Antimicrobial Agents for Wound Healing)
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