Advances in Animal Models in Biomedical Research, 3rd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (30 April 2025) | Viewed by 657
Special Issue Editor
Interests: animal studies; atrial fibrillation; autonomic nervous system; cardiac arrhythmias; cardiac remodeling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Preclinical studies have always represented, and will continue to represent, one of the pillars of medical progress. From William Harvey’s description of blood circulation to the elucidation of mechanisms that underlie atherosclerosis, cardiac arrhythmia, or heart failure, and to the development of heart transplantation, valve replacement, or coronary artery bypass grafting, all major medical breakthroughs have relied on studies performed in laboratory animals. Whether we are discussing the elucidation of physiological or pathophysiological mechanisms, the identification of new therapeutic targets, the evaluation of the efficacy and safety of new therapeutic strategies, or simply the organ and tissue resources that they represent, animals are indisputably an invaluable resource for progress in human medicine. Unfortunately, for numerous reasons, not all results obtained in animal studies end up being confirmed in humans. Choosing the right animal species, using the adequate model, and applying rigorous methodology and statistical tests are therefore critical in animal experimentation.
For this Special Issue, we invite both original research articles and reviews that provide the readers of IJMS with novel data regarding the most relevant animal models used in biomedical research.
Prof. Dr. Alina Scridon
Guest Editor
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Keywords
- animal experimentation
- in vivo animal studies
- interspecies differences
- standardization of animal models
- statistical analyses in animal studies
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