Molecular Underpinnings of Schizophrenia Spectrum Disorders, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 855
Special Issue Editors
Interests: psychiatric research; schizophrenia; neuroscience; mental health; schizophrenia spectrum disorders
Special Issues, Collections and Topics in MDPI journals
Interests: schizophrenia; psychoses; neuroimaging; omic sicence; mental health
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Schizophrenia spectrum disorders have a lifetime prevalence of 0.5–1% and remain among the top 15 causes of years lived with disability worldwide. They strongly affect the functioning and quality of life of patients and their loved ones. The difficulties resulting from these disorders also generate economic problems in the form of considerable direct and, mainly, indirect costs. The molecular alterations underlying schizophrenia and related disorders are only partially understood. Therefore, studying the molecular biology of this group of psychiatric conditions is of great scientific interest. In particular, the disorder encompasses various symptoms and lies at the interface between neurodevelopment and neuroprogression processes affecting the central nervous system (CNS). Omics sciences and artificial intelligence are revolutionizing the way we approach the biology of complex biological systems such as the CNS and its disorders. Applying these methods to patients with schizophrenia spectrum disorders might provide exciting insights into their pathophysiology, clarify the relationship between specific molecular findings and various symptom domains, and open new avenues for identifying possible new molecular targets.
We invite researchers in this field to submit original research articles or reviews that describe and discuss the most recent advances and developments in the molecular underpinnings of schizophrenia spectrum disorders.
Potential topics include, but are not limited to, the following:
- Genetic or genomic studies on schizophrenia spectrum disorders;
- Epigenetic or transcriptomic studies on schizophrenia spectrum disorders;
- Proteomic and metabolomic studies on schizophrenia spectrum disorders;
- Molecular studies on schizophrenia applying deep learning techniques;
- Studies that correlate the symptoms or cognitive characteristics of schizophrenia spectrum disorders with molecular aspects.
Prof. Dr. Paola Rocca
Dr. Claudio Brasso
Guest Editors
Manuscript Submission Information
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Keywords
- schizophrenia spectrum disorders
- central nervous system (CNS)
- psychotic disorders
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