Innovative Research on Nutrition and Epigenetics in Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 182
Special Issue Editor
Interests: SPME; GC-MS; extractives; compounds; cancer; tumor; treatment; cancer cells; Western blotting; flow cytometry; metabolic profile; apoptosis; cell cycle; drug; synthetic molecules
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
As we age, we undergo reversible epigenetic changes. DNA methylation and hydroxymethylation, RNA methylation, histone methylation, acetylation, and other modifications, as well as various RNA types, including microRNAs, mediate these alterations. Both intrinsic and extrinsic variables, such as the cell microenvironment of a tissue, can cause epigenetic changes. Lifestyle, nutrition, and the environment all play a significant part in this process. Recent studies suggest that epigenetic regulation could potentially contribute to the development of cancer progenitor cells, even though the current paradigm in carcinogenesis primarily focuses on successively selected mutations. Mutations control the rate and timing of the cancer’s progression. Additionally, several cancer hallmarks may be regulated by epigenetic processes. Although many cancer patients can become cancer-free thanks to current therapy, patients frequently relapse because these treatments do not eradicate cancer progenitors or stem cells. Because epigenetic medicines have the ability to destroy cancer progenitor cells, prevent the production of new cancer progenitor cells, and kill drug-resistant cancer cells, they are anticipated to decrease cancer relapse when used as part of combination therapy. Epigenetics is highly influenced by the environment, including diet, which is a source of metabolic substrates that influence the synthesis of cofactors or substrates for chromatin- and RNA-modifying enzymes. In addition, nutrition and diet are common sources of bioactives that can directly modify the activity of these enzymes. In this regard, a thorough investigation of how nutrition and food affect epigenetic changes is necessary.In this Special Issue, entitled "Innovative Research on Nutrition and Epigenetics in Cancer", original research articles and reviews are welcome to be submitted.We look forward to receiving your contributions.
Dr. Marisabel Mecca
Guest Editor
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Keywords
- diet
- nutrition
- epigenetics
- cancer
- cancer therapy
- lifestyle
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