Inflammation and Neurological Diseases: Molecular Mechanism and Emerging Therapy

Dear Colleagues,

Neuroinflammation plays a central role in the onset and progression of numerous neurological disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD), multiple sclerosis (MS), and traumatic brain injury (TBI). Growing evidence indicates that inflammation and dysregulated immune responses within the central nervous system (CNS) contribute to neuronal damage, synaptic dysfunction, and neurodegeneration. This Special Issue aims to provide a comprehensive overview of the molecular and cellular mechanisms linking inflammation to neurological pathologies, highlighting novel biomarkers, signaling pathways, and therapeutic targets. Contributions exploring innovative therapeutic strategies—such as anti-inflammatory drugs, biologics, gene and cell therapies, and lifestyle interventions—are particularly welcome. By integrating basic, translational, and clinical perspectives, this Special Issue seeks to advance understanding of how modulating inflammatory processes can prevent or mitigate neurological damage. We encourage submissions from researchers in neuroscience, immunology, pharmacology, and related disciplines to foster interdisciplinary dialogue and the development of emerging therapies for inflammation-related neurological diseases.

This Special Issue welcomes original research articles and reviews.

Dr. Sarah Adriana Scuderi
Dr. Deborah Mannino
Guest Editors

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