Protons in Biochemical Systems
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biophysics".
Deadline for manuscript submissions: closed (30 January 2024) | Viewed by 249
Special Issue Editor
Interests: computational biochemistry; molecular dynamics; bioenergetics; proton pumps; respiratory chains; molecular docking
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Protons play a fundamental role in biochemistry and biology. Reactions involving proton transfer are ubiquitous, ranging from enzyme catalysis and transport systems to reactions generating proton gradients in energy transduction systems. Unlike other biochemical actors, protons are very particular; they are the smallest atomic particles and the smallest ions in aqueous solution. In biochemical systems, they are still the subject of intense study, particularly, their extraordinarily high mobility in water, their behavior at interfaces, and their involvement in redox reactions. The concentration of protons has significant effects on biochemical thermodynamics, on the kinetics of reactions, and on the structure of macromolecules. An in-depth understanding of the processes involving protons in biochemistry and their homeostasis is not only important to elucidate the basic mechanisms involving this particle, but also has significant potential practical biomedical and biotechnological implications.
This Special Issue aims to provide an arena to present the most recent advances in the study of protons in biochemistry from a theoretical, experimental, and applied point of view. Research articles, communications, and reviews will be considered.
Potential topics include, but are not limited to: Protons in aqueous systems and at interfaces; proton diffusion in biochemical systems; the involvement of protons in reactions of biochemical interest; protons in energy transduction; the effect of protons on the structure of macromolecules; mechanisms of pH control and homeostasis; computational and experimental techniques for the study of protons in biochemical systems; the importance of protons in biomedical and biotechnological applications.
Prof. Dr. Luigi Leonardo Palese
Guest Editor
Manuscript Submission Information
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Keywords
- proton
- proton diffusion
- aqueous proton
- proton transfer
- enzyme catalysis
- pH
- structure
- protein
- macromolecules
- interface
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