Proteins and Mutations: Inherited Diseases, Drug Resistance and Pharmacogenomics
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 5465
Special Issue Editors
Interests: structural bioinformatics and its applications to drug discovery
Interests: study of genomic variation as predictive or prognostic markers in the context of drug therapies
Special Issue Information
Dear Colleagues,
Genetic variations that result in changes in amino acids can have striking effects on proteins. These effects can lead to inherited diseases; cause drug resistance in both communicable and non-communicable diseases; and play an important role in pathogenicity and infectivity, among many other biological phenomena. Hence, deciphering the impact of mutations, particularly missense mutations, on protein structure and function would help to understand their effects, which would ultimately guide the design of safer and more effective therapies or the safer use of current treatments. In this context, this Special Issue aims to cover different aspects of mutations and their structural as well as functional effects on proteins, and welcomes contributions from, but not limited to, biochemical, computational, and structural studies in the form of original research articles or up-to-date reviews.
Prof. Dr. Ozlem Tastan Bishop
Prof. Dr. Carlo R. Largiadèr
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- allostery
- cancer
- drug metabolism
- drug resistance
- drug and vaccine development
- infectious diseases
- missense mutations
- pathogenicity
- pharmacogenomics
- rare diseases
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.