Determinants of Chronic Diseases: Cellular Mechanisms and the Role of Natural Compounds
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 18
Special Issue Editor
Interests: metabolic pathways; antimicrobial; phenolics; photosystems
Special Issue Information
Dear Colleagues,
Chronic diseases, including cardiovascular disorders, neurodegeneration, and diabetes, constitute a major global health burden. The pathogenesis of these conditions is frequently driven by specific cellular determinants, such as sustained inflammation, oxidative stress, mitochondrial dysfunction, and dysregulated signaling pathways. Understanding how to intercept these cellular adaptations is critical for developing effective therapeutic strategies.
This Special Issue, “Determinants of Chronic Diseases: Cellular Mechanisms and the Role of Natural Compounds,” focuses on the mechanistic insights into how bioactive natural products modulate these cellular processes. We invite researchers to submit original research and review articles that clarify the molecular and cellular targets of natural compounds. Key topics include, but are not limited to, antioxidant defense mechanisms, anti-inflammatory signaling, the modulation of cell cycle arrest, induction of apoptosis, or autophagy. By bridging the gap between natural product chemistry and cellular biology, this collection aims to highlight novel avenues for preventing and managing chronic pathologies through nature-derived interventions.
Dr. Andrei Lobiuc
Guest Editor
Manuscript Submission Information
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Keywords
- chronic diseases
- natural compounds
- cellular mechanisms
- bioactive molecules
- signal transduction
- oxidative stress
- inflammation
- apoptosis
- mitochondrial dysfunction
- therapeutic targets
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