Molecular Design of Electrospun Fibers with Natural Bioactives for Biomedical Application
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 68
Special Issue Editor
Interests: electrospun biomaterials; polymeric hydrogels and polyHIPEs; photo-crosslinkable polymers; wound healing materials; emulsion-templated porous polymers; stereolithography (SLA)
Special Issue Information
Dear Colleagues,
Electrospun fibrous materials have attracted considerable attention in recent years due to their unique structural features, including high surface area, interconnected porosity, and morphological similarity to the extracellular matrix. These characteristics make them highly suitable for biomedical applications such as wound healing, tissue engineering, and localized drug release. At the same time, there has been a growing shift toward the use of naturally derived bioactive compounds—such as essential oils, terpenes, and plant-based extracts—owing to their intrinsic antibacterial, antioxidant, and anti-inflammatory properties. However, the practical application of these bioactives remains challenging due to their volatility, chemical instability, and rapid, uncontrolled release. Integrating such compounds into electrospun fiber systems offers a promising route to stabilize these agents and modulate their release behavior.
This Special Issue aims to highlight recent advances in the molecular design and functional development of electrospun fibers incorporating natural bioactives. We encourage contributions that focus on the relationship between material design and biological performance, including strategies to improve stability, controlled release, and therapeutic efficacy. Original research and review articles addressing innovative fiber architectures (e.g., core-shell, composite, or multifunctional systems), bioactive loading approaches, and applications in biomedical fields are particularly welcome. Studies supported by detailed physicochemical characterization and, where applicable, biological evaluation are especially encouraged. Through this collection, the Special Issue seeks to provide a focused yet comprehensive perspective on emerging directions in bioactive electrospun materials.
Dr. Fatma Nur Parın
Guest Editor
Manuscript Submission Information
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Keywords
- electrospun fibers
- molecular design
- natural bioactives
- core-shell nanofibers
- functional biomaterials
- controlled drug release
- wound healing
- tissue scaffolds
- stimuli-responsive systems
- antimicrobial polymers
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