Novel Therapeutic Strategies Targeting Cancer Stem Cells
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 28 May 2026 | Viewed by 24
Special Issue Editor
Special Issue Information
Dear Colleagues,
The cancer stem cell (CSC) hypothesis for tumorigenesis proposes that cancers arise in tissue stem and/or progenitor cells through dysregulation of the process of self-renewal. CSCs are a rare cell subpopulation found in several solid tumors, proliferate slowly, are endowed with self-renewal, are multipotent and highly tumorigenic. CSCs are also resistant to conventional anti-cancer treatments, including chemotherapy and ionizing radiations, thus being involved in disease recurrence and metastasis during tumor progression. To date, the main barriers for the development of CSCs-targeted therapies are their scarcity in vivo, the lack of fully reliable markers and, therefore, of specific CSCs-targeting agents (stemotoxic). We welcome submissions regarding novel approaches for CSCs detection, characterization and therapeutic strategies based on CSCs-specific molecular markers, including the use of biomaterials for in situ treatment of tumors.
Dr. Luciano Vellón
Guest Editor
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Keywords
- cancer stem cells
- machine learning
- deep learning
- therapeutic response
- molecular markers
- cancer
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