Emerging Insights into the Pathobiology and Biomarkers of Traumatic Brain Injury (TBI)
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 19
Special Issue Editor
Interests: traumatic brain injury and recovery mechanisms; blood-based biomarkers of neuronal and glial injury; post-traumatic stress and comorbid neuropsychiatric conditions; neuroinflammation and neurodegeneration after TBI; precision medicine approaches in neurological disorders
Special Issue Information
Dear Colleagues,
Traumatic brain injury (TBI) remains a leading cause of death and disability worldwide, yet our understanding of its pathobiology and long-term outcomes continues to evolve. Despite advances in imaging and clinical assessment, there is an urgent need for reliable biomarkers that can improve diagnosis, stratify injury severity, and guide targeted interventions across the acute, subacute, and chronic phases of TBI.
This Special Issue, Emerging Insights into the Pathobiology and Biomarkers of Traumatic Brain Injury (TBI), will bring together cutting-edge research and perspectives from molecular biology, neuroimmunology, neurodegeneration, and clinical sciences. We welcome contributions that explore the mechanisms underlying neuronal and glial injury, neuroinflammation, axonal degeneration, and neurovascular disruption, as well as studies that identify and validate biomarkers with translational potential for predicting outcomes, monitoring recovery, and guiding therapeutic development.
Original research articles, reviews, and perspectives that integrate genomic, proteomic, metabolomic, and imaging approaches are particularly encouraged. By highlighting emerging insights, this Special Issue will accelerate the discovery of biomarkers and mechanistic pathways that can transform care for individuals with TBI.
Prof. Dr. Jessica Gill
Guest Editor
Manuscript Submission Information
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Keywords
- traumatic brain injury (TBI)
- blood-based biomarkers
- neuroinflammation
- axonal injury
- neurodegeneration
- precision medicine
- omics approaches (genomics, proteomics, metabolomics)
- translational neuroscience
- TBI recovery and outcomes
- neurovascular injury
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