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Molecular Mechanism and Innovative Therapeutic Approaches in Gliomas: Translating Bench to Bedside

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 30 October 2025 | Viewed by 10

Special Issue Editors


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Guest Editor
Department of Neuroscience “Rita Levi Montalcini”, Neurosurgery Unit, University of Turin, 10126 Turin, Italy
Interests: brain tumor;spinal lesions

E-Mail Website
Guest Editor
Neurosurgery Unit, Department of Neuroscience, University of Turin, Turin, Italy
Interests: neurobiology; neurobiology and brain physiology; neurodegeneration; synaptic plasticity; neuroanatomy; neurodegenerative diseases; neural plasticity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Gliomas remain among the most aggressive and treatment-resistant brain tumours, posing significant challenges for both researchers and clinicians. This Special Issue will focus on tumour heterogeneity, genetic and epigenetic alterations, microenvironmental interactions, and resistance mechanisms. It will also highlight emerging therapies, including targeted treatments, immunotherapy, gene therapy, and nanomedicine. Of particular interest, this Special Issue will explore how these discoveries impact surgical decision making, intraoperative strategies, and overall patient management—making it highly relevant for specialists involved in the multidisciplinary care of glioma patients. By bridging basic and translational science with real-world clinical practice, this Special Issue aims to foster a deeper integration between laboratory discoveries and therapeutic innovations at the bedside.

This Special Issue is supervised by Dr. Cofano and Professor Garbossa and assisted by our Guest Editor Assistant, Dr. Panico (flavio.panico@unito.it, Università degli Studi di Torino, Turin, Italy).

Dr. Fabio Cofano
Prof. Dr. Diego Garbossa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • glioma
  • low-grade glioma
  • high-grade glioma
  • glioblastoma
  • tumor microenvironment
  • therapeutic resistance
  • molecular biomarkers
  • targeted therapy

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Published Papers

This special issue is now open for submission.
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