Infrared and Raman Spectroscopy of Human Diseases: 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biophysics".
Deadline for manuscript submissions: closed (15 September 2024) | Viewed by 4286
Special Issue Editors
2. Chemical Engineering School, Radiation Chemistry & Biospectroscopy, National Technical University of Athens, Zografou Campous, 15780 Athens, Greece
Interests: infrared and Raman spectroscopy; biospectroscopy; radiation chemistry; oxidative stress
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2. Teaching Assistant, Department of Chemistry, the University of Toronto, Toronto, ON M5S 2E8, Canada
3. Director of Physical Chemistry Centre, National Hellenic Foundation, 15780 Athens, Greece
Interests: inorganic chemistry; physical chemistry; organometallic chemistry; Fourier transform infrared spectroscopy; Raman spectroscopy; metal complexes; metal contamination of DNA and RNA; environmental health issues; public health; material organization; materials chemistry; materials engineering; nanomaterials; X-ray diffraction; synthesis; proteins; membranes; climate change
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Special Issue Information
Dear Colleagues,
In the third millennium, in our advanced technological epoch, striking hygienic and medical cutting-edge progress notwithstanding, microorganisms and non-infectious diseases still threaten human lives. SARS-CoV-2 has knocked thousands of health workers out of action worldwide. Science has also been affected, with studies paused in the majority of cases because data collection on surgical conditions in a pandemic crisis is difficult. Meetings, congresses, and courses have been cancelled or rescheduled as virtual. Meaningful research is necessary in order to compare the impact of diseases that have been affecting humanity from more than a decade (swine flu) to more than a century (tuberculosis). Today, more than ever after our experience with COVID-19, it is necessary to apply science, particularly molecular science, to the research and study of human diseases.
Infrared (IR) and Raman (RS) spectroscopy are used herewith to research human diseases at a molecular level. IR and RS are complementary; contrary to other detection diagnostic optical methods, both allow for a simultaneous analysis of all the components of the human tissues, liquid materials, or single cells, at a molecular level, without any specific preparation of the samples as in histopathology. Specific spectra of the biological molecules can be used to locate characteristic bands called “marker bands” in “fingerprint” regions in order to distinguish the native (healthy) state from the diseased one.
The spectra of biological molecules are sensitive to structural changes induced by the environment of these molecules and various affecting diseases including splachnic cancer (skin, breast, etc.), musculoskeletal neoplasms (benign and malignant bone and soft tissue tumors, and metastatic bone disease), cardiovascular diseases (coronary artery disease, atheromatosis, heart valve disease), diabetes mellitus, amyloidosis, and neurological diseases (Alzheimer and Parkinson). Additionally, since IR and RS are non-destructive, easy, and simple methods that require extremely small amounts of tissue samples for analysis, they can be used intraoperatively for rapid diagnosis of surgical margins after tumor resection surgery.
In the last decade, there has been a plethora of papers devoted to the research and study of many medical applications used to predict abnormalities induced by the disease and its progression as it deteriorates the health of the person. Therefore, we scheduled this Special Issue with the aim of collecting original papers, educative reviews, technical papers, and other forms of scientific communication on the molecular science of human disease.
Prof. Dr. Jane Anastassopoulou
Prof. Dr. Theophile Theophanides
Guest Editors
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Keywords
- infrared spectroscopy
- Raman spectroscopy
- biological molecules
- diseases
- orthopaedics
- medicine
- diagnosis
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