Novel Approaches for Tissue Repair and Tissue Regeneration
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (20 April 2026) | Viewed by 9931
Special Issue Editor
Interests: injuries; tissue repair; tissue regeneration; tissue engineering; tissue bioengineering; bioactive biomaterial; cell and gene therapeutics; hydrogel; immune modulation
Special Issue Information
Dear Colleagues,
Tissue repair and regeneration represent both critical and complex challenges in modern medicine. As the field continues to advance, there is a growing body of evidence supporting the potential of biomaterials and stem cells in facilitating tissue reconstruction and promoting regenerative processes. However, despite these promising developments, existing therapeutic strategies remain suboptimal, often falling short in fully addressing the intricate needs of tissue repair. To overcome these limitations, there is an urgent need for novel and innovative approaches that focus on enhancing the structural, biochemical, and mechanical properties of biomaterial scaffolds. These improvements are essential to better support the complex requirements of tissue growth, functional restoration, and integration within the body. Given these considerations, the current Special Issue seeks to invite research articles that explore emerging trends, cutting-edge methodologies, and new insights in the field of tissue engineering and regenerative medicine.
Key topics of interest for this Special Issue include, but are not limited to, the following:
- Engineered Biomaterials: Development of advanced biomaterials with tailored properties to mimic the native extracellular matrix and promote optimal tissue regeneration.
- Bioengineered Cells and Tissues: Innovative strategies for the engineering of cells and tissues, including the use of stem cells, growth factors, and genetic modifications to enhance tissue functionality.
- Slow and Local Delivery of Bioactive Molecules: Approaches that utilize controlled release systems to deliver bioactive molecules (such as growth factors, cytokines, and small molecules) in a spatially and temporally regulated manner to promote tissue repair and regeneration.
- 3D Bioprinting Approaches for Functionalized Tissue Constructs: The use of 3D bioprinting technologies to create complex, functional tissue constructs that closely replicate native tissue architecture and functionality.
- Interdisciplinary Pre-Clinical and Clinical Research for Nervous System Regeneration: Collaborative efforts between fields such as neurobiology, materials science, and bioengineering to advance therapeutic strategies for regenerating both the peripheral and central nervous systems.
This Special Issue aims to provide a platform for cutting-edge research that will pave the way for more effective therapies in tissue engineering and regenerative medicine. We encourage contributions that propose novel methodologies, highlight current challenges, and offer potential solutions that could transform clinical applications in regenerative healthcare.
Dr. Srinivas Madduri
Guest Editor
Manuscript Submission Information
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Keywords
- injuries
- tissue repair
- tissue regeneration
- tissue engineering
- tissue bioengineering
- bioactive biomaterial
- cell and gene therapeutics
- hydrogel
- immune modulation
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