Molecular Biomarkers in Oral Pathology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 July 2026 | Viewed by 3
Special Issue Editors
2. Department of Oral and Maxillofacial Surgery, Specialized Cancer Treatment and Reconstruction Center, Aristotle University of Thessaloniki, Thessaloniki, Greece
Interests: oral and maxillofacial surgery; biology of head and neck pathology
2. Department of Oral and Maxillofacial Surgery, Specialized Cancer Treatment and Reconstruction Center, Aristotle University of Thessaloniki, Thessaloniki, Greece
Interests: head and neck cancer; head and neck reconstruction; microsurgery; maxillofacial pathology; maxillofacial trauma; maxillofacial infections; advanced head and face implantology; cleft and orthognathic surgery; biomarkers; microRNA; tongue cancer
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Special Issue Information
Dear Colleagues,
It is with great pleasure that we introduce this Special Issue of Molecular Biomarkers in Oral Pathology, dedicated to advancing our understanding of the molecular signatures that underpin diseases of the oral cavity. Despite significant progress in genomics, proteomics, and precision medicine, the routine clinical application of molecular biomarkers in oral pathology remains limited. This gap underscores the need for rigorous investigations that illuminate the biological mechanisms driving oral disease and identify measurable indicators with diagnostic, prognostic, or therapeutic utility.
Oral pathology encompasses a diverse spectrum of disorders affecting the oral cavity and its adjacent structures, ranging from benign and malignant neoplasms—including oral cancer, odontogenic tumors, and salivary gland pathology—to infectious conditions and manifestations of systemic or autoimmune disease in the head and neck region. The complexity and heterogeneity of these conditions call for molecular tools capable of enhancing diagnostic accuracy, refining risk stratification, and guiding targeted therapeutic strategies.
According to the U.S. Food and Drug Administration, a biomarker is a defined characteristic that reflects biological processes and may predict clinical events, disease recurrence, or progression in affected patients. Within the context of oral pathology, molecular biomarkers may serve multiple roles:
- Diagnostic—identifying differences between healthy and diseased tissues;
- Prognostic—distinguishing molecular patterns associated with divergent clinical outcomes;
- Therapeutic—revealing actionable molecular pathways that can be modulated for disease intervention.
This Special Issue brings together contributions that explore these domains, with an emphasis on cutting-edge molecular analyses, innovative methodologies, and translational relevance. Our goal is to provide a comprehensive overview of current discoveries while stimulating further research that will ultimately integrate molecular biomarkers into everyday clinical practice.
We warmly invite researchers and clinicians to submit original research articles, comprehensive reviews, and brief communications that contribute to this growing field. The Special Issue is supervised by Dr. Ioannis Astreidis, with the valuable support of our Topical Advisory Panel Member, Assistant Professor Konstantinos Paraskevopoulos (Aristotle University of Thessaloniki, Greece).
We look forward to your contributions and to the scientific dialogue that will undoubtedly emerge from this collection.
Dr. Ioannis Astreidis
Dr. Konstantinos Paraskevopoulos
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- oral disease
- oral pathology
- oral cancer
- biomarkers
- molecular biomarkers
- head and neck pathology
- precision medicine
- omics-based analysis
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