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Research on Inflammation and Autophagy

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 30 October 2025 | Viewed by 26

Special Issue Editors


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Guest Editor
Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università degli Studi di Messina, Messina, Italy
Interests: cancer; neuro-oncology; neurodegenerative diseases; pharmacology; inflammation; apoptosis
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Dipartimento di Scienze Biologiche e Ambientali, Università degli Studi di Messina, Messina, Italy
Interests: neurodegeneration; neuroinflammation; oxidative stress; CNS trauma; cell death
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to highlight recent advances in our understanding of the dynamic interplay between inflammation and autophagy, two essential biological processes involved in health and disease. Autophagy, a highly conserved cellular mechanism for degrading and recycling cytoplasmic components, plays a crucial role in modulating immune responses and maintaining cellular homeostasis. Conversely, dysregulated inflammation can impair autophagic flux, leading to the progression of numerous pathological conditions, including cancer, neurodegenerative disorders, metabolic syndromes, and autoimmune diseases. Current research is uncovering the molecular pathways that link autophagy to inflammatory signaling, such as mTOR, NF-κB, and the inflammasome. This Special Issue welcomes original research articles and comprehensive reviews that explore the molecular mechanisms, functional consequences, and therapeutic implications of the autophagy–inflammation axis. By bringing together insights from basic and translational research, this Special Issue aims to foster a deeper understanding of the interconnected roles of autophagy and inflammation in disease pathogenesis and treatment.

Dr. Irene Paterniti
Dr. Michela Campolo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inflammation
  • autophagy
  • mTOR signaling
  • inflammasome
  • oxidative stress
  • acute and chronic inflammatory diseases

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Published Papers

This special issue is now open for submission.
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