Kidney Disease: Molecular Insights and Emerging Therapies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 November 2025) | Viewed by 263
Special Issue Editor
Special Issue Information
Dear Colleagues,
Kidney diseases represent a growing global health burden, with limited therapeutic options to halt or reverse disease progression. This special issue aims to highlight the latest discoveries in the molecular mechanisms underlying kidney pathologies and to feature cutting-edge therapeutic strategies under investigation. We welcome original research articles and comprehensive reviews that elucidate key cellular pathways, molecular regulatory networks, and pathogenic variants contributing to the development and progression of kidney diseases.
Particular emphasis will be placed on translational studies exploring innovative therapeutic approaches, including gene therapy platforms such as adeno-associated virus (AAV) vectors, CRISPR/Cas-based genome editing, RNA-targeting therapies, and other molecular interventions. Studies employing advanced experimental models—such as transgenic animals, organoids, or patient-derived cell systems—to validate novel targets and therapeutic mechanisms are especially encouraged. By bridging molecular insights with therapeutic innovation, this special issue seeks to foster the development of precise and effective treatments for both inherited and acquired forms of kidney disease.
Dr. Yaochun Zhang
Guest Editor
Manuscript Submission Information
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Keywords
- kidney disease
- molecular mechanism
- precision medicine
- translational nephrology
- targeted molecular therapy
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