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Exposure Science and Toxicology for Infants; Anthropogenic and Naturally Produced...
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Exposure Science and Toxicology for Infants; Anthropogenic and Naturally Produced Environmental Pollutants, Pharmaceuticals and Personal Care Products

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Environmental Health".

Deadline for manuscript submissions: closed (24 March 2023) | Viewed by 7137

Special Issue Editors

Prof. Dr. Yukiko Fujii

E-Mail Website
Chief Guest Editor
Department of Pharmaceutical Science, Daiichi University of Pharmacy, Fukuoka 815−8511, Japan
Interests: per- and polyfluoroalkyl substances; persistent organic pollutants; naturally occurring halogenated compounds; exposure to environmental chemicals; exposure through food; analytical chemistry
Dr. Junxia Yan

E-Mail Website
Guest Editor
Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410083, China
Interests: environmental epidemiology; chronic disease; genetic epidemiology; exposure science; health effect
Dr. Hyeran Yang

E-Mail Website
Guest Editor
Seoul Metropolitan Government Research Institute of Public Health and Environment, Gyeonggi-do 13818, Republic of Korea
Interests: biomonitoring of EDCs (Endocrine Disrupting Chemicals); dietary risk assessment; mycotoxins; environmental health; health impact assessment of air pollutants

Special Issue Information

Dear Colleagues,

Younger and more immature individuals have different responses to environmental factors, compared to adults. Although infants are considered vulnerable to chemicals, there are still many unknowns in this area. Infants are exposed to anthropogenic and naturally produced pollutants from foods, including human breast milk. Moreover, several pharmaceuticals were found in human breast milk, which may cause a biological effect in infants. Personal care products (PCPs) are also a concern. After the use of PCPs, they may spread in the indoor environment, so they are exposed to infants. More insights from exposure science and the toxicology of these chemicals concerning infants are needed to elucidate the health effects and health promotion.

This special issue, therefore, covers both exposure science and toxicological study for infants. We welcome manuscripts from different disciplines that aim to elucidate the health effects in infants; chemical exposures in humans, in vivo and in vitro toxicological studies, and health impact assessment/management. Solid though preliminary studies are welcomed if they have the potential to stimulate and contribute to environmental health for infants. Fundamental criteria for acceptance is that the study is original, scientifically sound and provides valuable knowledge which will lead to new insights or hypothesis to future studies. As well as the original articles, we also welcome other types of articles such as reviews, study protocols and project reports as an integration and update of current knowledge. This special issue will help elucidate environmental health for infants, which is a still unclear research domain.

Dr. Yukiko Fujii
Dr. Junxia Yan
Dr. Hyeran Yang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • infants
  • exposure science
  • toxicology
  • environmental health
  • pollutants
  • personal care products

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Published Papers (3 papers)

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8 pages, 10296 KiB  
Article
Teratogenic Effects of Organohalogen Contaminants Extracted from Whale Bacon in a Whole-Rat-Embryo Culture System
by Masaharu Akita, Osamu Kimura, Kazutaka Atobe, Tetsuya Endo, Shizuo Yamada, Koichi Haraguchi and Yoshihisa Kato
Int. J. Environ. Res. Public Health 2022, 19(19), 12065; https://doi.org/10.3390/ijerph191912065 - 23 Sep 2022
Cited by 1 | Viewed by 1730
Abstract
Marine foods can be contaminated with organochlorines and the risk to human beings who consume these foods needs to be evaluated. We examined the teratogenic effects of contaminants extracted from whale bacon on rat embryos using a whole-embryo culture system. Embryonic day 11.5 [...] Read more.
Marine foods can be contaminated with organochlorines and the risk to human beings who consume these foods needs to be evaluated. We examined the teratogenic effects of contaminants extracted from whale bacon on rat embryos using a whole-embryo culture system. Embryonic day 11.5 embryos were cultured for 48 h with organohalogens extracted from whale bacon at low (polychlorinated biphenyls (PCBs): 0.32 ppm, dichlorodiphenyltrichloroethanes (DDTs): 0.16 ppm, chlordanes (CHLs): 0.02 ppm) and high (PCBs: 2.15 ppm, DDTs: 1.99 ppm, CHLs: 0.20 ppm) doses. The levels of organohalogen compounds in cultured embryos were determined. The organochlorine contaminants extracted from whale products were readily transferred to the cultured rat embryos. The number of heartbeats, yolk sac circulation score, and embryonic body circulation score of embryos did not change during the culture period in either exposure group. Cultured embryos treated with the low-dose contaminated medium for 48 h showed abnormalities of the mandible, and craniofacial or forelimb hematomas with an incidence of 50%. All embryos treated with the high-dose medium showed craniofacial abnormalities and cleft lip, and limb abnormalities and hematomas. These results indicate that the organohalogen contaminants in whale bacon may be teratogenic in a dose-dependent manner. Further studies are necessary to determine the dose–effect relationship. Full article
(This article belongs to the Special Issue Exposure Science and Toxicology for Infants; Anthropogenic and Naturally Produced Environmental Pollutants, Pharmaceuticals and Personal Care Products)
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13 pages, 2858 KiB  
Perspective
A Study on the Preliminary Plan for Environmental Health in Seoul, Korea
by Jong-Seok Won, Hyomi Kim and Sang-Gyoon Kim
Int. J. Environ. Res. Public Health 2022, 19(24), 16611; https://doi.org/10.3390/ijerph192416611 - 10 Dec 2022
Cited by 1 | Viewed by 1711
Abstract
In the Republic of Korea, the Environmental Health Act was amended in January 2021, making it mandatory for each local government to establish a plan for environmental health. Accordingly, the Seoul Metropolitan Government (SMG) must establish the Local Plan for Environmental Health (LPEH) [...] Read more.
In the Republic of Korea, the Environmental Health Act was amended in January 2021, making it mandatory for each local government to establish a plan for environmental health. Accordingly, the Seoul Metropolitan Government (SMG) must establish the Local Plan for Environmental Health (LPEH) to protect citizens’ health from environmental hazards. The plan would support existing environmental health policies in Seoul to improve population health and achieve their goals. As a proof-of-concept to establish the LPEH, we developed a preliminary plan for environmental health in Seoul. We analyzed environmental health conditions of Seoul, identified driving conditions for execution of environmental health policies, set basic policy directions, and identified tasks needed to establish the preliminary plan. As a result, we established the vision and the goals of the preliminary plan. The vision is “a safe Seoul environment, healthy citizens”. The strategies are “active monitoring of environmental health issues”, “minimization of health damage and meticulous and systematic response”, and “building a foundation for environmental health”. To achieve the vision and the goals, we developed three strategies, eight tasks, and 25 sub-tasks. Under the preliminary plan we developed, we expect that SMG is able to protect citizens’ health from threats of environmental hazards; improve environmental health conditions, especially in susceptible populations such as infants; and promote environmental justice. Full article
(This article belongs to the Special Issue Exposure Science and Toxicology for Infants; Anthropogenic and Naturally Produced Environmental Pollutants, Pharmaceuticals and Personal Care Products)
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6 pages, 285 KiB  
Study Protocol
Systematic Review Protocol for the Current State of Chemical Exposure in Infants via Breast Milk, Artificial Milk and Dairy Products
by Manal A. M. Mahmoud, Hosnia Abdel-Mohsein, Usama Mahmoud, Zhaoqing Lyu, Sani Rachman Soleman, Meng Li, Tomoko Fujitani, Mariko Harada Sassa, Yukiko Fujii, Yang Cao, Toshiaki Hitomi and Kouji H. Harada
Int. J. Environ. Res. Public Health 2021, 18(9), 4436; https://doi.org/10.3390/ijerph18094436 - 22 Apr 2021
Cited by 1 | Viewed by 2550
Abstract
Many studies have shown that human breast milk is contaminated with various chemicals. In the proposed systematic review, the aim is to identify and summarize the available literature regarding chemical exposure via breastfeeding or the feeding of artificial formula. MEDLINE (PubMed) will be [...] Read more.
Many studies have shown that human breast milk is contaminated with various chemicals. In the proposed systematic review, the aim is to identify and summarize the available literature regarding chemical exposure via breastfeeding or the feeding of artificial formula. MEDLINE (PubMed) will be the primary source in this literature search. Primary studies that analyzed one or more chemicals of interest in breast milk or artificial milk and that reported information on concentrations will be eligible for this review. Conference abstracts will not be included in the review unless access to the data is easy. First, the titles and abstracts of identified articles will be screened by two or more researchers. Then, a full-text review will be conducted to extract data from the included articles and code them for classification. The results of the search and classification will be summarized narratively and bibliometrically. The aim of the review is to analyze trends in publications according to year and region from the viewpoint of target chemicals, location, range of concentrations, and health outcomes. Full article
(This article belongs to the Special Issue Exposure Science and Toxicology for Infants; Anthropogenic and Naturally Produced Environmental Pollutants, Pharmaceuticals and Personal Care Products)
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