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Healthcare
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Preventive and Management Strategies in Modern Obstetrics
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Preventive and Management Strategies in Modern Obstetrics

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: 30 November 2025 | Viewed by 992

Special Issue Editors

Dr. Ioannis Tsakiridis

E-Mail Website
Guest Editor
Third Department of Obstetrics and Gynecology, Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, Agiou Dimitriou, 54124 Thessaloniki, Greece
Interests: high-risk pregnancies; perinatal medicine; placental research; fetal medicine
Special Issues, Collections and Topics in MDPI journals
Dr. Themistoklis I. Dagklis

E-Mail Website
Guest Editor
3rd Department of Obstetrics and Gynecology, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Interests: maternal–fetal medicine; obstetrics; gynecology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Modern obstetrics has evolved significantly over recent decades, emphasizing preventive care and effective management strategies to ensure the best outcomes for both mothers and infants. With advancements in medical technology, evidence-based practices, and a holistic approach to maternal health, the field continues to refine its methods. Preconception care is crucial for identifying and managing risk factors before pregnancy. This includes health assessments, nutritional counseling, guidance on balanced nutrition, and lifestyle modifications. Specialized care for pregnancies with increased risk of complications includes a collaboration between obstetricians, perinatologists, and other specialists, and more frequent prenatal visits, ultrasounds, and non-stress tests to monitor fetal well-being. Furthermore, adjusting or introducing medications to manage conditions like preeclampsia or gestational diabetes is of paramount importance. To summarize, preventive and management strategies in modern obstetrics are fundamental to ensuring healthy pregnancies and deliveries. By focusing on preconception care, prenatal screening, vaccinations, and advanced management of high-risk pregnancies and deliveries, obstetric care providers can significantly improve outcomes for mothers and their babies. Continuous advancements in technology and a holistic approach to maternal health will undoubtedly continue to shape the future of obstetrics, making pregnancy and childbirth safer for all women.

This Special Issue aims to explore the key preventive and management strategies that define contemporary obstetric care.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Obstetrics;
  • Preventive strategies;
  • Management techniques;
  • Maternal–fetal medicine.

We look forward to receiving your contributions.

Dr. Ioannis Tsakiridis
Dr. Themistoklis I. Dagklis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • prevention
  • management
  • complications
  • obstetrics
  • maternal–fetal medicine

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Published Papers (1 paper)

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Research

10 pages, 342 KiB  
Article
Impact of Placental Grading on Pregnancy Outcomes: A Retrospective Cohort Study
by Antonios Siargkas, Ioannis Tsakiridis, Georgios Michos, Anastasios Liberis, Sofoklis Stavros, Menelaos Kyriakakis, Ekaterini Domali, Apostolos Mamopoulos and Themistoklis Dagklis
Healthcare 2025, 13(6), 601; https://doi.org/10.3390/healthcare13060601 - 10 Mar 2025
Viewed by 787
Abstract
Background: Placental grading remains underutilized in clinical practice despite its potential prognostic value. This study aimed to elucidate the relationship between premature placental calcification (PPC) and relevant perinatal outcomes in a large cohort. Methods: We conducted a retrospective cohort study involving 3088 singleton [...] Read more.
Background: Placental grading remains underutilized in clinical practice despite its potential prognostic value. This study aimed to elucidate the relationship between premature placental calcification (PPC) and relevant perinatal outcomes in a large cohort. Methods: We conducted a retrospective cohort study involving 3088 singleton pregnancies that underwent routine third-trimester ultrasound examinations (30+0 to 35+6 gestational weeks) at the Third Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece, between January 2018 and December 2023. Placental calcification was graded using the Grannum system, categorizing placentas into Grades 0–1 (control), Grade 2, and Grade 3. Primary outcomes assessed were small for gestational age neonates (SGA) and preeclampsia. Secondary outcomes included gestational hypertension, fetal growth restriction (FGR), stillbirth, gestational age at birth, and birthweight centile. Multiple logistic regression was employed to adjust for confounders, i.e., maternal age, BMI, smoking, conception via assisted reproductive technology, and uterine artery pulsatility index. Results: In total, 544 pregnancies (17.6%) had Grade 2 placentas, and 41 pregnancies (1.3%) had Grade 3 placentas. Compared to the control group, Grade 2 placentas were associated with increased odds of SGA (adjusted odds ratio [aOR] 1.80; 95% confidence intervals [CI]: 1.43–2.25) and FGR (aOR 1.81; 95% CI: 1.35–2.42). Grade 3 placentas showed even higher odds of SGA (aOR 3.09; 95% CI: 1.55–6.17) and FGR (aOR 3.26; 95% CI: 1.53–6.95). No significant associations were found between placental grading and preeclampsia or stillbirth. Additionally, PPC was linked to lower birthweight percentiles and earlier gestational age at birth. Conclusions: Premature placental calcification (before 36+0 weeks), particularly Grade 3, is significantly associated with adverse perinatal outcomes such as SGA and FGR. Incorporating placental grading into routine prenatal care may enhance risk stratification and guide clinical decision making beyond traditional assessment methods. Full article
(This article belongs to the Special Issue Preventive and Management Strategies in Modern Obstetrics)
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