Artificial Intelligence and Public Health: From Predictive Models to Preventive Actions

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Public Health and Preventive Medicine".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 871

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Department of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy
Interests: public health; environmental health; preventive medicine; epidemiology; healthcare preparedness; risk communication
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Special Issue Information

Dear Colleagues,

The integration of artificial intelligence (AI) into public health is one of the most significant paradigm shifts of the past decade. AI and machine learning systems are increasingly capable of processing complex, multidimensional health data ranging from environmental exposures and disease surveillance indicators to behavioral and social determinants of health. This transformation is redefining how we understand, prevent, and manage health challenges at the individual, community, and population levels.

Despite remarkable progress, many questions remain open. How can AI-based predictive models truly improve prevention rather than just prediction? How can digital tools and intelligent systems support decision-making in real-world public health contexts—balancing innovation with ethics, transparency, and equity? And how can data-driven approaches contribute to healthier environments, communities, and lifestyles?

The aim of this Special Issue is to bridge the gap between population-level public health research and practical healthcare system applications, promoting the integration of AI-driven insights into clinical and preventive decision-making. We particularly welcome studies that go beyond descriptive epidemiology to apply AI-based models for prediction, prevention, and decision support in both healthcare practice and public health policy. Contributions may include research on AI for disease surveillance, early intervention, and health promotion; studies exploring the integration of environmental and social determinants into healthcare decision-making; and investigations addressing the ethical, regulatory, and equity dimensions of AI implementation.

Particular attention will be given to interdisciplinary studies that connect AI with healthcare systems, public health policy, and the “human-centered” design of digital solutions.

In this Special Issue, original research papers, systematic reviews, methodological studies, and perspectives are all welcome. Research areas may include (but are not limited to) the following:

  • Predictive modelling and machine learning for disease prevention and healthcare decision support;
  • AI-based disease surveillance and risk forecasting for communicable and noncommunicable diseases;
  • Data-driven approaches to health promotion and behavior change in clinical and community settings;
  • Digital decision-support tools for healthcare management, policy, and resource planning;
  • The integration of AI with social, clinical, and health system datasets to enhance prevention and patient care;
  • AI applications for population health monitoring and early intervention strategies;
  • Ethical, regulatory, and equity dimensions of AI adoption in healthcare and public health practice.

We look forward to receiving your contributions.

Dr. Marco Dettori
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial intelligence
  • public health
  • health systems
  • machine learning
  • predictive models
  • disease surveillance
  • digital health
  • health promotion
  • health equity

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Published Papers (1 paper)

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Review

23 pages, 3205 KB  
Review
Artificial Intelligence in Social Health: A Narrative Review of Uses, Advantages, Challenges, and Future Directions
by Yousif M. Elmosaad
Healthcare 2026, 14(14), 2114; https://doi.org/10.3390/healthcare14142114 - 14 Jul 2026
Viewed by 285
Abstract
Artificial intelligence (AI) is deeply integrated into daily life. Emerging evidence suggests AI may help change the dynamics of social relationships by influencing social interactions, connectivity, and interpersonal relationships, and by providing new avenues for communication and contributing to improved social well-being. Therefore, [...] Read more.
Artificial intelligence (AI) is deeply integrated into daily life. Emerging evidence suggests AI may help change the dynamics of social relationships by influencing social interactions, connectivity, and interpersonal relationships, and by providing new avenues for communication and contributing to improved social well-being. Therefore, this review aims to explore the potential of artificial intelligence (AI) technologies as a tool to enhance social health, focusing on current applications, advantages, challenges, and ethical considerations associated with their implementation, as well as opportunities for future development. The literature on the relationship between the connectedness of social health dimensions and AI as a tool to better understand how interactions with AI technologies may influence social well-being. In this current review, key terms such as “Artificial Intelligence”, “Social Health”, “social inequalities”, “AI algorithm”, “AI technology”, “social connection”, “digital communication”, “social participation”, “social support”, “social isolation”, “loneliness”, “mental wellbeing”, were used to search relevant literature on Google Scholar, PubMed, Scopus and Web of Sciences. In addition, relevant aspects of the multidimensional impacts of AI on social health dimensions are also discussed. The use of AI technologies by individuals within societies was found to hold profound potential to reshape social health through enhancing social relationships, bridging communication gaps in diverse populations, stimulating social dynamics, and understanding human emotions. It may contribute to reducing social inequalities, promoting equity, accommodating individual differences, and enhancing the effectiveness of many tasks in the social and health care systems through deep learning, natural language processing, and machine learning techniques. This reduces social exclusion and increases accessibility and quality of health and social services. However, AI has also posed distinguishable challenges to its adoption, specifically in terms of data quality, privacy and security, algorithmic bias, ethical issues, public trust and acceptance, and regulatory and policy gaps. Evidence suggests that building public trust in the future of AI in social health requires interdisciplinary collaboration among health providers and professionals, social scientists, community members, and policymakers. Such collaboration is crucial to ensure that AI platforms do not perpetuate social inequalities or biases by maintaining transparency, explainability, and demonstrated effectiveness. In conclusion, the integration of AI into social health dimensions holds promise for social health transformation. As we move forward, several key areas need to be addressed to develop a robust governance and regulatory framework, along with ethical guidelines to ensure privacy protection, respect for human rights, transparency, and the promotion of the common good. Full article
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