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Genes publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Decoding the Epigenomic Basis of Gene Regulation in Cancer

edited by Alireza Lorzadeh

submission deadline 15 Apr 2027 | Viewed by 30 | Submission Open

Keywords: epigenetic enhancer dynamics; epigenetic stem cell plasticity; epigenetic single-cell multi-omics; epigenetic disease heterogeneity; epigenetic gene regulatory networks; AI-driven epigenetic analysis; epigenetic precision medicine

(This special issue belongs to the Section Epigenomics)

Epigenomic and Genomic Studies of Cancers

edited by Yuxiang Wang

submission deadline 20 Apr 2027 | Viewed by 278 | Submission Open

Keywords: cancer; mutation; amplification; deletion; epigenetics; 3D epigenetics; next-generation sequencing; ChIP-seq; Hi-C; DamID; sequential FISH; SPRITE; GAM

(This special issue belongs to the Section Epigenomics)

Genomics, Climate Adaptation and Precision Breeding in Animals

edited by

Themistoklis Giannoulis

submission deadline 20 Apr 2027 | Viewed by 54 | Submission Open

Keywords: climate adaptation; genomic selection; livestock genomics; heat stress; precision breeding; sustainability

(This special issue belongs to the Section Animal Genetics and Genomics)

Advances in Genetic Insights into Cardiovascular Diseases

edited by

John Alex Elefteriades

submission deadline 25 Apr 2027 | Viewed by 37 | Submission Open

Keywords: cardiovascular genetics; causative genes; whole exome sequencing; genotype–phenotype correlation; precision therapy; pharmacogenetics in CVD; gender medicine in CVD

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Bioinformatics of Genome Regulation

edited by

Kenta Nakai

Hongyan Xu

and

Martin Loza

submission deadline 25 Apr 2027 | Viewed by 26 | Submission Open

Keywords: epigenomics; transcriptional regulation; single-cell multi-omics; deep learning; gene regulatory networks; chromatin architecture; genome grammar

(This special issue belongs to the Section Bioinformatics)

Genetics and Gene Regulation of Atrial Fibrillation and Other Cardiology

edited by Weijia Luo

submission deadline 25 Apr 2027 | Viewed by 23 | Submission Open

Keywords: atrial fibrillation; cardiac arrhythmias; cardiomyopathies and heart failure; functional genomics; gene regulatory networks epigenetics and epigenomics; multi-omics integration; genome editing and CRISPR applications; biomarker discovery; precision medicine

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Genetic Mechanisms of Hormonal Regulation in Insect Development and Metamorphosis

edited by

Tao Geng

submission deadline 25 Apr 2027 | Viewed by 22 | Submission Open

Keywords: insect development; insect metamorphosis; hormonal regulation; gene regulation; behavior; epigenetics

(This special issue belongs to the Section Animal Genetics and Genomics)

DNA Replication Fidelity and Dynamics in Cancer

edited by

Francesca Citron

submission deadline 25 Apr 2027 | Viewed by 18 | Submission Open

Keywords: DNA replication; DNA damage and repair; epigenetics; genomic instability; immune response; immunotherapy; tumor evolution

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advanced Research in Forensic Genetics—2nd Edition

edited by

Mauro Pesaresi

submission deadline 10 May 2027 | 2 articles | Viewed by 1343 | Submission Open

Keywords: forensic genetics; massive parallel sequencing (MPS); DNA quantification methods; DNA extraction methods; sudden cardiac death; post-mortem interval; microRNA; DNA phenotyping; individual identification; genetic markers; short tandem repeats (STR); single nucleotide polymorphism (SNP); mitochondrial DNA (mtDNA); microhaplotype; forensic statistics; artificial intelligence; activity level in forensics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Alternative Splicing in Genetic Disorders and Cancer

edited by

Giuseppina Covello

submission deadline 10 May 2027 | Viewed by 569 | Submission Open

Keywords: alternative splicing (AS); genetic disorders; key cancer-related genes; aberrant splicing; therapeutic approaches

(This special issue belongs to the Section Molecular Genetics and Genomics)

Genomic and Molecular Mechanisms of Inherited Retinal Diseases: From Molecular Insights to Clinical Practice and Diagnosis

edited by

Raffaella Cascella

submission deadline 10 May 2027 | Viewed by 17 | Submission Open

Keywords: IRDs; genomics; molecular mechanisms; genetic diagnosis; genotype–phenotype correlation; high-throughput technologies (NSG, LRS); precision medicine; clinical translation; therapy

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Advances in CRISPR-Cas Genome Editing

edited by Lijun Cheng

submission deadline 10 May 2027 | Viewed by 13 | Submission Open

Keywords: CRISPR-Cas genome editing; CRISPR screening; functional genomics; CRISPR interference (CRISPRi); CRISPR activation (CRISPRa); synthetic lethality; artificial intelligence; precision medicine; single-cell genomics; spatial transcriptomics; drug discovery; RNA target discovery

(This special issue belongs to the Section Technologies and Resources for Genetics)

New Advances in Computational Regulatory Genomics

edited by

Sourav Roy

submission deadline 10 May 2027 | Viewed by 11 | Submission Open

Keywords: promoters; gene expression; gene regulation; GWAS; computational algorithms

(This special issue belongs to the Section Bioinformatics)

Hereditary Traits and Diseases in Companion Animals

edited by

Lucie Chevallier

and

Marie Abitbol

submission deadline 15 May 2027 | 5 articles | Viewed by 9548 | Submission Open

Keywords: genetic traits; hereditary diseases; companion animals; spontaneous disease models; veterinary genetics; genetic selection; breed-specific diseases

(This special issue belongs to the Section Animal Genetics and Genomics)

Animal Mating Strategies: Insight from Molecular Genetics

edited by Robert Rutkowski

submission deadline 15 May 2027 | Viewed by 16 | Submission Open

Keywords: animal mating strategies; sexual selection; reproductive success; parentage analysis; kinship and relatedness; molecular ecology; evolutionary ecology; extra-pair patternity; conservation genetics

(This special issue belongs to the Section Animal Genetics and Genomics)

Advances in Genetics and Genomics of Complex Traits and Diseases

edited by Irman Forghani

submission deadline 15 May 2027 | Viewed by 15 | Submission Open

Keywords: complex traits and diseases; polygenic risk and prediction; genome‑wide and sequencing‑based studies; multi‑omics and integrative genomics; functional genomics and variant interpretation; gene–environment interactions; translational genomics and clinical implementation; precision medicine and risk stratification; diverse populations and health equity

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Pathogenic Variants and Genomic Mechanisms in Diseases

edited by Arpad M. Danos

submission deadline 15 May 2027 | Viewed by 11 | Submission Open

Keywords: variant interpretation; bioinformatics; mathematical biology; CIViC knowledgebase

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Plant Stress Biology and Crop Genetic Improvement: From Molecular Mechanisms to Breeding Applications

edited by

Xinjie Shen

submission deadline 15 May 2027 | Viewed by 2 | Submission Open

Keywords: abiotic stress tolerance; biotic stress resistance; multi-omics integration; key gene identification; CRISPR/Cas9 gene editing; epigenetic regulation; improvement of stress, yield, and quality; root biology and resource efficiency; phytohormone signaling; germplasm evaluation and utilization; secondary metabolites in defense; genomic selection and prediction; phenomics and high-throughput screening; AI and machine learning; phenotypic plasticity

(This special issue belongs to the Section Plant Genetics and Genomics)

Genomic and Molecular Determinants of HPV-Related Reproductive Health

edited by

Nektaria Zagorianakou

and

Efthalia Moustakli

submission deadline 20 May 2027 | 1 articles | Viewed by 1072 | Submission Open

Keywords: human papillomavirus (HPV); viral genomics; epigenomics; proteomics; vaginal microbiome; intestinal microbiome; metabolic pathways; oxidative stress; infertility genetics; reproductive health; personalized medicine; precision medicine; AI-driven diagnostics

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Gene Expression Perturbations and In Vitro Systems in Applied Toxicology: From Measurement to Biological Interpretation

edited by Bhaja Krushna Padhi

submission deadline 20 May 2027 | Submission Open

Keywords: gene expression; alternative splicing; mRNA biomarkers; targeted transcriptomics; molecular toxicology; gene orthology; in vitro toxicology; chemical toxicity assessment; regulatory toxicology; new approach methodologies (NAMs)

(This special issue belongs to the Section Toxicogenomics)

Advances in Omics of Arthropod Vectors

edited by

Xiufeng Zhang

, Yoonseong Park, Kristopher Silver and Dana Mitzel

submission deadline 15 Jun 2027 | Viewed by 27 | Submission Open

Keywords: arthropod vectors; pest control; pathogen interactions; vector biology; genes; genomics; epigenomics; genetics; animal health; crop protection

(This special issue belongs to the Section Animal Genetics and Genomics)

Genomic and Genetic Determinants of Liver Health and Disease

edited by Ralf Weiskirchen

submission deadline 15 Jun 2027 | Submission Open

Keywords: liver genetics; human genomics; metabolic liver disease; MASLD/MASH genetics; hepatocellular carcinoma genetics; genomic biomarkers; precision hepatology; GWAS and sequencing; functional genomics; liver disease susceptibility

(This special issue belongs to the Section Human Genomics and Genetic Diseases)

Displaying special issue 201-250 on page 5 of 5.

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