Computational Genomics and Bioinformatics of Cancer

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Bioinformatics".

Deadline for manuscript submissions: 20 February 2026 | Viewed by 11

Special Issue Editor


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Guest Editor
Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada
Interests: gene regulation; computational biology; bioinformatics; genomics; algorithms
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Special Issue Information

Dear Colleagues,

Cancer is one of the deadliest illnesses in the modern world, with multiple challenges for diagnosis, treatment, and patient survival. Yet it is also one of the most enigmatic illnesses with numerous possible causes and factors involved.

Cancer belongs to the category of complex diseases (related to multiple genes, their modifications (both genetic and epigenetic) and regulation, and environmental factors.

In this sense, it is similar to other complex diseases, such as heart disease, diabetes, autoimmune and psychiatric diseases. From scientific standpoint, it may be the most complex disease, often characterized as a family of multiple illnesses, not just one.

This makes cancer formidable scientific challenge. Huge amounts of data, originating from multiple and various sources, should be obtained, classified, and analyzed, to result in practical recommendations. Bioinformatically, this is highly multidimensional task, with all the respective problems and challenges involved.

The present issue invites original research papers and reviews that address this tremendous problem, either in general or in the specific aspects.

We hope that besides understanding the cancer(s) it will be helpful in understanding complex diseases in general.

Dr. Ilya Ioshikhes
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cancer
  • data analysis
  • bioinformatics
  • complex diseases
  • dimensionality reduction
  • genetics
  • epigenetics
  • gene regulation
  • molecular mechanism
  • environmental factors

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Published Papers

This special issue is now open for submission.
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