Special Issue "Gene Therapy"
Deadline for manuscript submissions: closed (31 October 2016) | Viewed by 31371
Interests: gene-based vaccines; gene therapy; oncolytic virotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue in Biomedicines: Gene Therapy for Hereditary Diseases
Special Issue in Vaccines: Gene-Based Vaccines
Many gene therapy and genetic vaccine vectors are non-replicating agents. If they deliver one transgene to the cell, they then express ³1X² of the transgene protein. While replication-defective vectors can be potent, replication-competent vectors can surpass this potency by replicating transgenes in each cell to amplify therapeutic or vaccine responses. In many cases, apples and oranges comparisons of replication-defective and replication-competent vectors are performed. This issue will discuss vectors with and without replicating functions with particular emphasis on head to head comparisons of replication-defective, single-cycle, and replication-competent vectors.
Prof. Dr. Michael A. Barry
Manuscript Submission Information
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- Gene Therapy
- Gene-based Vaccines
- Cancer Gene Therapy
- Cancer Vaccines
- Cancer Immunotherapy