Next Article in Journal
Identification of Novel Equine (Equus caballus) Tendon Markers Using RNA Sequencing
Next Article in Special Issue
Magnetofection Enhances Lentiviral-Mediated Transduction of Airway Epithelial Cells through Extracellular and Cellular Barriers
Previous Article in Journal
Steric Clash in the SET Domain of Histone Methyltransferase NSD1 as a Cause of Sotos Syndrome and Its Genetic Heterogeneity in a Brazilian Cohort
Open AccessReview

Gene Therapy: A Paradigm Shift in Dentistry

Department of Oral Biology, Bahria University Medical and Dental College, Karachi 75260, Pakistan
Department of Biomedical Engineering, College of Engineering, King Faisal University, Al-Hofuf 31982, Saudia Arabia
Department of Restorative Dentistry, College of Dentistry, Taibah University, Madina Munawwarrah 41311, Saudi Arabia
Author to whom correspondence should be addressed.
Academic Editor: Michael Barry
Genes 2016, 7(11), 98;
Received: 28 July 2016 / Revised: 16 October 2016 / Accepted: 3 November 2016 / Published: 10 November 2016
(This article belongs to the Special Issue Gene Therapy)
Gene therapy holds a promising future for bridging the gap between the disciplines of medicine and clinical dentistry. The dynamic treatment approaches of gene therapy have been advancing by leaps and bounds. They are transforming the conventional approaches into more precise and preventive ones that may limit the need of using drugs and surgery. The oral cavity is one of the most accessible areas for the clinical applications of gene therapy for various oral tissues. The idea of genetic engineering has become more exciting due to its advantages over other treatment modalities. For instance, the body is neither subjected to an invasive surgery nor deep wounds, nor is it susceptible to systemic effects of drugs. The aim of this article is to review the gene therapy applications in the field of dentistry. In addition, therapeutic benefits in terms of treatment of diseases, minimal invasion and maximum outcomes have been discussed. View Full-Text
Keywords: gene therapy; pain; cancer; DNA vaccination; bone repair; tooth repair; orthodontic tooth movement gene therapy; pain; cancer; DNA vaccination; bone repair; tooth repair; orthodontic tooth movement
Show Figures

Graphical abstract

MDPI and ACS Style

Siddique, N.; Raza, H.; Ahmed, S.; Khurshid, Z.; Zafar, M.S. Gene Therapy: A Paradigm Shift in Dentistry. Genes 2016, 7, 98.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop