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Special Issue "Evolutionary Medicine"
Deadline for manuscript submissions: closed (31 May 2018).
Interests: human population genetics; human evolution; bioinformatics; analysis of genetic diversity; population substructure; algorithms
Interests: Population genetics; human genomics; evolutionary biology; bioinformatics; species evolution ; adaptation; natural selection; Deep Learning; Approximate Bayesian Computation
Evolutionary medicine focuses on interpreting health and disease from an evolutionary perspective by using the well-established evolutionary framework and the currently available plethora of methods and tools developed in the fields of evolutionary genetics and population genetics. Understanding health and disease has traditionally focused on identifying the molecular and physiological mechanisms that caused a disease and, based on this knowledge, proposing strategies for alleviating and reverting the disease symptoms. In all of this, understanding the ultimate roots of illness—why evolution has shaped these mechanisms in ways that may leave us susceptible to a particular disease—has been mostly neglected and/or ignored. However, this question is particularly relevant in human species. First of all, humans evolved to live as hunter-gatherers in small tribal bands—a very different way of life and environment compared to that faced by contemporary humans. This change makes present-day humans vulnerable to a number of health problems, termed “disease of civilization”. Second, as humans multiplied and spread across the planet, they encountered thousands of local variations in diet and disease that generated diverse selection pressures. Those selection pressures wrote varied signatures on the locally diverging genomes; finally, drift and founder events added to the genetic divergence of local populations’ susceptibility to particular diseases.
This issue will address questions that advance the intellectual development of linkages between evolutionary biology and medical science, focusing on evolutionary explanations for human susceptibility to disease, suggesting improvements connected to evolutionary mechanisms in clinical practice, public health procedures, research approaches, or medical education and being of interest to clinicians, public health professionals, medical researchers and educators, and evolutionary biologists.
Dr. Oscar Lao
Dr. Olga Dolgova
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- evolutionary medicine
- thrifty gene hypothesis
- health and disease
- positive selection