DNA Origami and Aptamer Assemblies
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Technologies and Resources for Genetics".
Deadline for manuscript submissions: closed (1 October 2018) | Viewed by 49243
Special Issue Editors
Interests: chemistry; aptamers; thioaptamers; cancer; 3D printing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
In the last decade, the field of DNA origami has gone from infancy to a field with a suite of building techniques for creating a wide variety of structures. Using DNA building blocks formed into wedges, bricks, and tubes, complex 3D objects can be created. Indeed, an object over a billion daltons has been made. Other methods using fractal assembly or bacteriophages can create complicated machines containing built-in DNAzymes to act as molecular scissors to create scaffolds with custom voids, hinges, designer apertures, or even nanorobots. Although creating shapes like a mini Mona Lisa or a rabbit is interesting, the next phase of DNA origami seeks to develop tools that are useful as diagnostic agents or drug delivery vehicles, at a large scale and at a reasonable cost. In this regard, the combination of DNA origami with aptamer assemblies or complimentary aptamer pairs may play a role, as could further developments in predictive software.
In this Special Issue, we welcome original research or review articles on any topic related to “DNA Origami and Aptamer Assemblies”. We look forward to your contributions.
Dr. David VolkDr. Varatharasa Thiviyanathan
Guest Editors
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Keywords
- DNA origami
- aptamer
- DNA cage
- macromolecular structures
- computational biology
- diagnostic agents
- drug delivery vehicles
- DNAzymes
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