Special Issue "DNA Origami and Aptamer Assemblies"
Deadline for manuscript submissions: closed (1 October 2018)
Dr. David E. Volk
In the last decade, the field of DNA origami has gone from infancy to a field with a suite of building techniques for creating a wide variety of structures. Using DNA building blocks formed into wedges, bricks, and tubes, complex 3D objects can be created. Indeed, an object over a billion daltons has been made. Other methods using fractal assembly or bacteriophages can create complicated machines containing built-in DNAzymes to act as molecular scissors to create scaffolds with custom voids, hinges, designer apertures, or even nanorobots. Although creating shapes like a mini Mona Lisa or a rabbit is interesting, the next phase of DNA origami seeks to develop tools that are useful as diagnostic agents or drug delivery vehicles, at a large scale and at a reasonable cost. In this regard, the combination of DNA origami with aptamer assemblies or complimentary aptamer pairs may play a role, as could further developments in predictive software.
In this Special Issue, we welcome original research or review articles on any topic related to “DNA Origami and Aptamer Assemblies”. We look forward to your contributions.Dr. David Volk
Dr. Varatharasa Thiviyanathan
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- DNA origami
- DNA cage
- macromolecular structures
- computational biology
- diagnostic agents
- drug delivery vehicles