Genetic and Molecular Insights into Cardiovascular Disease: From Mechanisms to Precision Medicine
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: 15 December 2025 | Viewed by 66
Special Issue Editors
Interests: atherosclerosis; cardiovascular disease; cardio-oncology; and genetic epidemiology
Interests: microRNA; chronic kidney disease; erythriopoiesis; cardiovascular disease; gene regulation; multi-omics; miR-223; biomarker
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiovascular disease (CVD) remains a leading cause of global morbidity and mortality, with genetic and molecular factors playing pivotal roles in its development, progression, and treatment. Advances in genomics, transcriptomics, and epigenetics have revealed novel pathways and biomarkers, offering unprecedented opportunities in precision medicine. This Special Issue, "Genetic and Molecular Insights into Cardiovascular Disease: From Mechanisms to Precision Medicine", will showcase cutting-edge research and reviews exploring the genetic and molecular basis of CVD. Topics of interest include, but are not limited to, the following:
- Genetic variants and pathways driving CVD risk and outcomes;
- Epigenetic modifications (e.g., DNA methylation, histone modifications) in CVD pathogenesis;
- The role of non-coding RNAs (e.g., miRNAs, lncRNAs) in cardiovascular biology;
- Integration of polygenic risk scores (PRSs) and Mendelian randomization (MR) for causal inference and risk prediction;
- Translational applications of genetic and molecular diagnostics in personalized CVD management (e.g., the sex gap in CVD).
We welcome original research articles, reviews, and perspectives exploring the genetic and molecular mechanisms behind CVD and their implications for precision medicine. This Special Issue will provide a platform for researchers to share insights into the genetic architecture of CVD and its potential in transforming clinical practice.
Dr. Lingfeng Luo
Prof. Dr. Laurent Metzinger
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cardiovascular disease
- genetic variants
- precision medicine
- epigenetics
- non-coding RNAs
- polygenic risk scores
- mendelian randomization
- biomarkers
- genome-wide association studies (GWASs)
- molecular mechanisms
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