Gel Film and Its Wide Range of Applications

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Applications".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 3730

Special Issue Editors


E-Mail Website
Guest Editor
Institute of Biological Science, University of Pernambuco (UPE), Recife 50670-901, Brazil
Interests: gels; biochemistry, biotechnology, characterization of biomolecules, polymeric matrices

E-Mail Website
Guest Editor
Biochemistry Department, Federal University of Pernambuco, Recife 50670-901, Brazil
Interests: gels; biochemistry, biotechnology, nanotechnology, polymeric matrices, biological engineering

E-Mail Website
Guest Editor
Biochemistry Department, Federal University of Pernambuco, Recife 50670-901, Brazil
Interests: gels; biochemistry, biotechnology, characterization of biomolecules, polymeric matrices

Special Issue Information

Dear Colleagues,

Gels are defined as solid three-dimensional networks, consisting of the external structure and a medium within. Although the medium can be a gas, it can also be a fluid. In the second option, the matrix can be classified as a hydrogel when it can absorb and retain water without dissolving. The hydrogel resistance to dissolution arises from cross-links between network chains, while their ability to absorb water arises from the hydrophilic functional groups distributed along the polymeric backbone.

This Special Issue aims to report a collection of articles dealing with the synthesis, characterization, and different applications of new hydrogels. For this purpose, the content includes polymeric matrices being developed and characterized, evaluated using in vitro and/or in vivo studies, and also clinical research applied to synthetic or natural-based hydrogels.

The publication of original research articles, rapid communications, or reviews in this Special Issue will be of significant contribution to the scientific knowledge of hydrogels.

Dr. Priscilla Barbosa Sales De Albuquerque
Dr. María G. Carneiro-Da-Cunha
Dr. Paulo Antônio Galindo Soares
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biotechnology
  • polymeric matrices
  • three-dimensional network
  • swelling
  • water content

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

37 pages, 16800 KiB  
Review
An Overview of Microorganisms Immobilized in a Gel Structure for the Production of Precursors, Antibiotics, and Valuable Products
by Dmitriy Berillo, Turganova Malika, Baiken B. Baimakhanova, Amankeldi K. Sadanov, Vladimir E. Berezin, Lyudmila P. Trenozhnikova, Gul B. Baimakhanova, Alma A. Amangeldi and Bakhytzhan Kerimzhanova
Gels 2024, 10(10), 646; https://doi.org/10.3390/gels10100646 - 10 Oct 2024
Cited by 2 | Viewed by 3410
Abstract
Using free microorganisms for industrial processes has some limitations, such as the extensive consumption of substrates for growth, significant sensitivity to the microenvironment, and the necessity of separation from the product and, therefore, the cyclic process. It is widely acknowledged that confining or [...] Read more.
Using free microorganisms for industrial processes has some limitations, such as the extensive consumption of substrates for growth, significant sensitivity to the microenvironment, and the necessity of separation from the product and, therefore, the cyclic process. It is widely acknowledged that confining or immobilizing cells in a matrix or support structure enhances enzyme stability, facilitates recycling, enhances rheological resilience, lowers bioprocess costs, and serves as a fundamental prerequisite for large-scale applications. This report summarizes the various cell immobilization methods, including several synthetic (polyvinylalcohol, polyethylenimine, polyacrylates, and Eudragit) and natural (gelatin, chitosan, alginate, cellulose, agar–agar, carboxymethylcellulose, and other polysaccharides) polymeric materials in the form of thin films, hydrogels, and cryogels. Advancements in the production of well-known antibiotics like penicillin and cephalosporin by various strains were discussed. Additionally, we highlighted cutting-edge research related to strain producers of peptide-based antibiotics (polymyxin B, Subtilin, Tyrothricin, varigomycin, gramicidin S, friulimicin, and bacteriocin), glusoseamines, and polyene derivatives. Crosslinking agents, especially covalent linkers, significantly affect the activity and stability of biocatalysts (penicillin G acylase, penicillinase, deacetoxycephalosporinase, L-asparaginase, β-glucosidase, Xylanase, and urease). The molecular weight of polymers is an important parameter influencing oxygen and nutrient diffusion, the kinetics of hydrogel formation, rigidity, rheology, elastic moduli, and other mechanical properties crucial for long-term utilization. A comparison of stability and enzymatic activity between immobilized enzymes and their free native counterparts was explored. The discussion was not limited to recent advancements in the biopharmaceutical field, such as microorganism or enzyme immobilization, but also extended to methods used in sensor and biosensor applications. In this study, we present data on the advantages of cell and enzyme immobilization over microorganism (bacteria and fungi) suspension states to produce various bioproducts and metabolites—such as antibiotics, enzymes, and precursors—and determine the efficiency of immobilization processes and the optimal conditions and process parameters to maximize the yield of the target products. Full article
(This article belongs to the Special Issue Gel Film and Its Wide Range of Applications)
Show Figures

Figure 1

Back to TopTop