Rational Design and Characterization of Hydrogels

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Analysis and Characterization".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 25

Special Issue Editors


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Guest Editor
Department of Mechanical and Aerospace Engineering, Syracuse University, Syracuse, NY 13244, USA
Interests: polymers; fibers and textiles; hydrogels; smart materials; bio-inspired design; personal thermal and moisture management; advanced materials for the built environment
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Special Issue Information

Dear Colleagues,

Recent progress in hydrogel research has moved beyond empirical formulation toward rational design strategies, where molecular architecture, crosslinking mechanisms, and hierarchical structures are deliberately engineered to achieve targeted performance. The rational design of hydrogels increasingly relies on a fundamental understanding of structure–property relationships. Advances in polymer chemistry, supramolecular interactions, dynamic reversible bonding, multi-network architectures, and advanced manufacturing have enabled precise control over mechanical strength, toughness, self-healing capability, responsiveness, and transport behavior.

Comprehensive characterization techniques play a central role in guiding rational hydrogel design. Modern techniques, including rheology, spectroscopy, scattering, microscopy, and mechanical testing, provide insights into network dynamics, crosslink evolution, and deformation mechanisms. Coupled with modeling and simulation, these tools enable quantitative evaluation of hydrogel behaviors, thereby guiding iterative design and optimization.

This Special Issue, “Rational Design and Characterization of Hydrogels”, aims to bring together cutting-edge research that bridges molecular design principles with advanced characterization methods. Contributions addressing novel hydrogel chemistries, multiscale characterization, structure–property correlations, and application-driven design are particularly welcome. By highlighting both fundamental advances and practical considerations, this collection seeks to provide a comprehensive perspective on how rational design and characterization can accelerate the development of next-generation hydrogels with enhanced functionality and reliability.

Dr. Lihong Lao
Dr. Ye Tian
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hydrogels
  • rational material design
  • structure–property relationships
  • multiscale characterization

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Published Papers

This special issue is now open for submission.
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