Recent Developments in Nanocomposite Hydrogels

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Applications".

Deadline for manuscript submissions: closed (31 January 2026) | Viewed by 1297

Special Issue Editors


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Guest Editor
Grupo de Compósitos e Nanocompósitos Híbridos (GCNH), São Paulo State University (Unesp), School of Engineering, Ilha Solteira 15385-000, SP, Brazil
Interests: polymers; pesticides; hydrogels; composites; controlled release
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Guest Editor
Faculdade de Engenharia, Universidade Estadual Paulista (UNESP), Ilha Solteira 15385-007, Brazil
Interests: active packaging; bionanocomposites; essential oils; nanoemulsions; edible films and coatings; nanocellulose; bacterial cellulose; hydrogels; nanoparticles
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Owing to their unique properties, such as adjustable physicochemical effects, sensitivity to external stimulus, biodegradability, biocompatibility, ease and low-cost synthesis, research addressing nanocomposite hydrogels has increased considerably in recent years. The incorporation of nanostructured fillers, including zeolite, cellulose nanofibers and nanocrystals, clay, nanoparticles and carbon nanotubes, into hydrogels has become an interesting strategy for enhancing some specific properties, particularly mechanical and hydrophilic properties, and sorption/absorption and release properties, among others.

The aim of this Special Issue is to present a collection of papers focused on recent advances and developments in nanocomposite hydrogels for application in a number of fields, including food, engineering, agricultural, medicine and health area, and others. This Special Issue will cover all nanocomposite hydrogels, including nanoclay- and zeolite-based nanocomposite hydrogels, 3D hydrogels, etc. All researchers working on nanocomposite hydrogels are invited to contribute their studies to this Special Issue.

Prof. Dr. Fauze Ahmad Aouada
Prof. Dr. Marcia Regina de Moura Aouada
Guest Editors

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Keywords

  • hydrogels
  • zeolite
  • nanoclay
  • nanoparticles
  • biodegradability
  • biocompatibility
  • innovative technology
  • natural polymers
  • controlled release
  • 3D printer

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Published Papers (1 paper)

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Research

18 pages, 1427 KB  
Article
Protein-Directed Nucleation and Stabilization of Ultrasmall Silver Nanoparticles Within BSA Hydrogels
by Carmen Salto-Giron, M. Carmen Gonzalez-Garcia, Mari C. Mañas-Torres, Modesto T. Lopez-Lopez, Luis Alvarez de Cienfuegos, Jose L. Hueso, Angel Orte and Emilio Garcia-Fernandez
Gels 2026, 12(3), 231; https://doi.org/10.3390/gels12030231 - 12 Mar 2026
Viewed by 542
Abstract
Biocompatible nanocomposite hydrogels are emerging as versatile platforms in nanomedicine, particularly when natural proteins are used as both structural and chemical components. In this work, we report a green, simple, and rapid in situ synthesis of ultrasmall silver nanoparticles (uAgNPs) within a bovine [...] Read more.
Biocompatible nanocomposite hydrogels are emerging as versatile platforms in nanomedicine, particularly when natural proteins are used as both structural and chemical components. In this work, we report a green, simple, and rapid in situ synthesis of ultrasmall silver nanoparticles (uAgNPs) within a bovine serum albumin (BSA) hydrogel, in which albumin simultaneously acts as the reducing agent and three-dimensional scaffold. The confined reaction environment generated uniformly dispersed Ag nanostructures with diameters in the 4–40 nm range, as confirmed by DLS and TEM. High-resolution TEM revealed clear Face-Centered Cubic (FCC, 111) lattice fringes, demonstrating the crystalline nature of the embedded uAgNPs. Quantitative image analysis showed narrow size distributions and high circularities, consistent with cluster stabilization through protein–metal interactions. Rheological measurements further indicated that the incorporation of uAgNPs enhanced hydrogel stiffness and delayed yielding, reflecting a reinforcement effect mediated by the nanoparticles acting as additional cross-linking points. Moreover, when very small embedded uAgNPs are formed, the presence of emissive silver nanoclusters was found using fluorescence emission spectroscopy. Overall, our results show that BSA hydrogels provide an effective matrix for directing green uAgNP nucleation, ensuring high stability, controlled growth in less than 2 min, and improved mechanical properties. The resulting protein–nanoparticle composite constitutes a promising soft material for imaging, sensing, and other biomedical applications requiring stable, biocompatible nanoscale architectures. Full article
(This article belongs to the Special Issue Recent Developments in Nanocomposite Hydrogels)
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