Challenges in Environmental and Occupational Monitoring: New Methods, New Chemicals, New Concerns for Safety and Health

A special issue of Environments (ISSN 2076-3298).

Deadline for manuscript submissions: 15 April 2026 | Viewed by 369

Special Issue Editors


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Guest Editor
Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL-National Institute for Insurance against Accidents at Work, 00078 Monteporzio Catone, Italy
Interests: endocrine disrupters; occupational exposure to chemicals; reprotoxicity
Special Issues, Collections and Topics in MDPI journals

E-Mail
Guest Editor
Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Istituto nazionale Assicurazione Infortuni sul Lavoro (INAIL), 00144 Roma, Italy
Interests: biological monitoring; biomarkers; occupational exposure; occupational and environmental health; oxidative stress
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Laboratory Risks of Chemical Agents, Istituto Nazionale Assicurazione Infortuni sul Lavoro (INAIL), 00078 Roma, Italy
Interests: occupational and environmental health; professional exposure to chemical agents as pollutants in various workplaces (as hazardous medical products and chemical substances in hospitals and in the veterinary sector, determination of polycyclic-aromatic hydrocarbons-PAHs emitted by granules or mulches used as infill material in synthetic turf pitches etc.)
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce this Special Issue entitled “Challenges in Environmental and Occupational Monitoring: New Methods, New Chemicals, New Concerns for Safety and Health”.

Exposure to chemicals, in daily and working settings, represents an issue of great importance for the protection of health and safety of workers as well as of the general population. New substances are increasingly being included in production cycles, and this requires new analytical methods capable of measuring their concentration levels and therefore the potential exposure of people. Knowing the new substances present in the market, in the workplace and in the environment, being able to quantitatively measure their presence in different matrices and characterizing the exposure for human beings are essential elements for subsequently evaluating the risks to human health.

The aims of the issue are as follows: (1) highlight the new analytical methods carried out to measure the concentrations levels of chemical contaminants both in environmental matrix and in biological fluids, to assess the exposure levels and the subsequent possible health risks; (2) identify new health effects linked to exposure to chemical agents, through the description of experimental investigations in vivo or in vitro or epidemiological investigations; (3) understand and identify the risks associated with the introduction of new substances into production cycles, both in terms of risks for workers and consumers.

Dr. Lidia Caporossi
Dr. Daniela Pigini
Dr. Paola Castellano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Environments is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chemical exposure
  • health risks
  • occupational exposure
  • contamination
  • analytical methods

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Published Papers (1 paper)

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Review

12 pages, 234 KiB  
Review
Trifluoroacetic Acid: A Narrative Review on Physico-Chemical Properties, Exposure Pathways, and Toxicological Concerns
by Andrea Moscato, Maria Valentina Longo, Margherita Ferrante and Maria Fiore
Environments 2025, 12(8), 277; https://doi.org/10.3390/environments12080277 - 12 Aug 2025
Viewed by 250
Abstract
Trifluoroacetic acid (TFA) is a persistent degradation product of widely used fluorinated compounds such as hydrofluorocarbons, hydrofluoroolefins, hydrochlorofluorocarbons (HCFCs) and hydrochlorofluoroolefins. Its chemical stability, water solubility, and environmental persistence raise concerns about potential human and ecological risks. To provide an overview of current [...] Read more.
Trifluoroacetic acid (TFA) is a persistent degradation product of widely used fluorinated compounds such as hydrofluorocarbons, hydrofluoroolefins, hydrochlorofluorocarbons (HCFCs) and hydrochlorofluoroolefins. Its chemical stability, water solubility, and environmental persistence raise concerns about potential human and ecological risks. To provide an overview of current knowledge on TFA, we conducted a literature search (PubMed and Scopus, December 2024–January 2025) focusing on its environmental fate, human exposure, toxicokinetic, ecotoxicology, and regulation. A narrative approach was applied, prioritizing recent and high-quality evidence. TFA is ubiquitous in air, water, food, and consumer products. Human exposure occurs mainly through ingestion and inhalation. It is rapidly absorbed and excreted mostly unchanged in urine, with limited metabolic transformation. Though not bioaccumulated in fat, its environmental persistence and ongoing exposure raise concerns about long-term systemic effects. Ecotoxicological data show chronic toxicity in aquatic and terrestrial species, with environmental concentrations often exceeding safety thresholds. Currently, no binding EU limit exists for TFA, although several countries have proposed drinking water guidelines. TFA represents an emerging environmental contaminant with potential human health and ecological impacts. Strengthened monitoring, long-term toxicological studies, and precautionary regulatory action are urgently needed. Full article
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