Special Issue "Applications of Topological Data Analysis in the Life Sciences"

A special issue of Entropy (ISSN 1099-4300). This special issue belongs to the section "Signal and Data Analysis".

Deadline for manuscript submissions: 30 November 2021.

Special Issue Editors

Prof. Dr. Kathryn Hess Bellwald
E-Mail Website
Guest Editor
SV BMI UPHESS, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland
Interests: algebraic topology; applications of topology in life sciences; category theory
Prof. Dr. Pablo G. Camara
E-Mail Website
Guest Editor
Department of Genetics and Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA
Interests: computational biology; single-cell biology; cancer genomics; topology and metric geometry applications

Special Issue Information

Topological data analysis (TDA) is a relatively new field of research, at the intersection of data science and algebraic topology, and it provides robust mathematical, statistical, and algorithmic methods to infer, analyze, and interpret the topological and geometric structures underlying complex data. TDA provides a set of powerful, efficient tools that can be used in combination with other data science methods. TDA techniques are applied primarily to point clouds in metric spaces, but can also be extended to geometric objects such as graphs. TDA has convincingly proved its utility in a wide range of applications in the life sciences, including in neuroscience, genomics, proteomics, evolution, and cancer biology, among other areas of research. Given these recent successes, the time is ripe for this Special Issue, devoted to surveying the remarkable insights into life sciences that have already been provided by TDA, and to explore promising new developments.

Prof. Dr. Kathryn Hess Bellwald
Prof. Dr. Pablo G. Camara
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Entropy is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • topological data analysis
  • genomics
  • proteomics
  • neuroscience
  • cancer biology
  • developmental biology
  • metabolomics

Published Papers

This special issue is now open for submission.
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