Role of the Tumor Microenvironment in Early Diagnosis of Cancers
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 354
Special Issue Editor
Interests: ovarian cancer; gynecological cancers; exosomes; tumor microenvironment; drug resistance; chemotherapy; tumor metabolism; drug screening; tumor organoids; cancer metastatsis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The tumor microenvironment (TME) consists of different cellular components, including tumor cells, stromal cells (e.g., fibroblasts), endothelial cells, immune cells (e.g., microglia, macrophages), and non-cellular components, i.e., the extracellular matrix (collagen, fibronectin, laminin, etc.). The dynamic interactions between the cellular and extracellular matrix components contribute to tumor heterogeneity, clonal evolution, emergence of drug resistance, tumor progression, and metastasis. Thus, it is important to understand these bi-directional interactions between tumor cells and their environment that can help to identify critical drivers of carcinogenesis and novel biomarkers that could help in early diagnosis.
This Special Issue will be dedicated to publishing original work and reviews that contribute to our understanding of the TME and its role in cancer diagnosis. Studies related to the function of the various TME components and their use in cancer diagnosis will be published. Further, studies involving the use of advanced imaging techniques, liquid biopsies, etc. will be most welcome. Studies pertaining to biomarker discovery, TME microvesicles and exosomes, and mechanism-based studies involving different TME structural components in the context of cancer diagnosis will be included in this Special Issue.
Dr. Samrita Dogra
Guest Editor
Manuscript Submission Information
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Keywords
- tumor microenvironment
- cancer diagnosis
- biomarker
- microvesicles
- exosomes
- TME components
- liquid biopsy
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