Role of the Tumor Microenvironment in Early Diagnosis of Cancers
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 258
Special Issue Editor
Interests: ovarian cancer; gynecological cancers; exosomes; tumor microenvironment; drug resistance; chemotherapy; tumor metabolism; drug screening; tumor organoids; cancer metastatsis
Special Issue Information
Dear Colleagues,
The tumor microenvironment (TME) consists of different cellular components, including tumor cells, stromal cells (e.g., fibroblasts), endothelial cells, immune cells (e.g., microglia, macrophages), and non-cellular components, i.e., the extracellular matrix (collagen, fibronectin, laminin, etc.). The dynamic interactions between the cellular and extracellular matrix components contribute to tumor heterogeneity, clonal evolution, emergence of drug resistance, tumor progression, and metastasis. Thus, it is important to understand these bi-directional interactions between tumor cells and their environment that can help to identify critical drivers of carcinogenesis and novel biomarkers that could help in early diagnosis.
This Special Issue will be dedicated to publishing original work and reviews that contribute to our understanding of the TME and its role in cancer diagnosis. Studies related to the function of the various TME components and their use in cancer diagnosis will be published. Further, studies involving the use of advanced imaging techniques, liquid biopsies, etc. will be most welcome. Studies pertaining to biomarker discovery, TME microvesicles and exosomes, and mechanism-based studies involving different TME structural components in the context of cancer diagnosis will be included in this Special Issue.
Dr. Samrita Dogra
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- tumor microenvironment
- cancer diagnosis
- biomarker
- microvesicles
- exosomes
- TME components
- liquid biopsy
