Insulin Therapy: New Technologies and Future Perspectives

A Special Issue of Diabetology (ISSN 2673-4540).

Deadline for manuscript submissions: closed (20 May 2026) | Viewed by 1247

Editor


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Guest Editor
University Hospitals Cleveland Medical Center, CWRU School of Medicine, Cleveland, OH, USA
Interests: type 1 diabetes; islet cell transplant and diabetes prevention and remission

Special Issue Information

Dear Colleagues,

This Special Issue will begin with the history of insulin therapy before delving into the issue’s focus on new technologies and future perspectives. Authors are invited to submit original research and review articles covering various facets of modern insulin treatment, including the following:

  • Short-acting and long-acting insulin formulations;
  • Innovations in dosing regimens;
  • Therapeutic inertia;
  • Pump and non-pump methods of delivering insulin;
  • Challenges and gaps in current insulin therapy practices;
  • The future of insulin management.

We welcome contributions that provide new insights, address current challenges, or present innovative approaches in the field.

Prof. Dr. Betul Hatipoglu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diabetology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • short-acting
  • long-acting
  • therapeutic inertia
  • pump insulin
  • non-pump insulin

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Published Papers (1 paper)

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Research

11 pages, 1076 KB  
Article
When Pancreas Transplant Recipients Gain Weight: Challenges in Endogenous Insulin Delivery
by Nina L. Owen-Simon, Geoffrey K. Dube, Lloyd E. Ratner and Kasi McCune
Diabetology 2026, 7(7), 136; https://doi.org/10.3390/diabetology7070136 - 15 Jul 2026
Viewed by 493
Abstract
Background/Objectives: To determine the association between post-pancreas transplantation weight gain and graft dysfunction. Methods: Retrospective analysis of pancreas transplantation from 1 August 2008 to 1 November 2022. All patients > 18 years old who underwent simultaneous kidney pancreas transplant (SPK), pancreas after kidney [...] Read more.
Background/Objectives: To determine the association between post-pancreas transplantation weight gain and graft dysfunction. Methods: Retrospective analysis of pancreas transplantation from 1 August 2008 to 1 November 2022. All patients > 18 years old who underwent simultaneous kidney pancreas transplant (SPK), pancreas after kidney transplant (PAK), and pancreas transplant alone (PTA) with at least one year of follow up were included. The association between post-transplant weight gain and graft dysfunction was assessed. Graft dysfunction was defined as HbA1c > 6.5% or use of antihyperglycemic medication. Results: Twenty-five percent of recipients had substantial weight gain (SWG), defined as >7% weight increase, by 1 year post-transplant. Recipients with T2D and SPK recipients were more likely to gain weight. SWG within the first year was significantly associated with the development of graft dysfunction at most recent follow up (Cox HR = 3.3, p = 0.005), but not at 1 year. Recipients with SWG in the first year had significantly higher HbA1C at most recent follow up (5.3 ± 0.7% vs. 5.9 ± 0.9%, p = 0.009), but not at 1 year. Among recipients with SWG occurring after 1 year, there were no differences in graft dysfunction or HbA1C at 1 year and no difference in graft dysfunction or HbA1C at most recent follow up. Conclusions: In this single-center study, SWG at 1 year post-transplant was associated with the development of graft dysfunction and elevated HbA1C in the long term. Full article
(This article belongs to the Special Issue Insulin Therapy: New Technologies and Future Perspectives)
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