Periodontal/Peri-Implant Inflammation and Systemic Conditions

Dear Colleagues,

Periodontal and peri-implant inflammation are multifactorial conditions increasingly linked to varied systemic diseases. Strong evidence supports bidirectional relationships between periodontal disease, peri-implantitis, and systemic conditions such as diabetes, cardiovascular disease, autoimmune disorders, respiratory diseases, and adverse pregnancy outcomes. Understanding these interactions is essential for improving diagnostic accuracy, risk assessment, and comprehensive patient care.

This Special Issue invites original research, clinical studies, and reviews that explore the biological, clinical, and epidemiological connections between oral inflammation and systemic health. Topics of interest include the impact of diabetes and other systemic disorders on periodontal and peri-implant tissue breakdown, host–microbiome interactions, inflammatory pathways, systemic biomarkers, and the effects of systemic medications on treatment outcomes. Contributions addressing innovative diagnostic tools, personalized prevention strategies, and interdisciplinary management approaches are particularly encouraged.

Dr. Piero Papi
Dr. Lorenzo Marini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.