Protein Crystallography: Achievements and Challenges

Dear Colleagues,

Proteins are the most important biological macromolecules and are involved in almost all aspects of life. Therefore, the study of the structure of proteins is of great practical and fundamental importance. On the one hand, knowledge of the spatial structure is necessary to study the basic principles of protein functioning, for example, the mechanisms of enzymatic reactions. On the other hand, knowledge of the spatial structure of proteins is used, for example, in biotechnology for the design of enzymes with desired properties, as well as in drag design. Today, the main method for determining the spatial structure of a protein is X-ray structural analysis of protein crystals. The main difficulty in applying this method is obtaining a highly perfect protein crystal. In this Special Issue, articles devoted to the description of the spatial structures of proteins, as well as articles devoted to the practical and theoretical aspects of improving the quality of protein crystals, are welcome.

Dr. Vladimir Timofeev
Dr. Hiroaki Tanaka
Dr. Yuri Pisarevsky
Dr. Margarita Marchenkova
Guest Editors

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