Crystal Structure and Properties of Multicomponent Pharmaceutical Materials

Dear Colleagues,

We are pleased to invite you to submit original research or review articles to this Special Issue that focuses on the “Crystal Structure and Properties of Multicomponent Pharmaceutical Materials”.

Multicomponent crystals of pharmaceutical materials include salts, cocrystals, and hydrates/solvates of active pharmaceutical ingredients (APIs). Recently, more sophisticated multicomponent forms of salt-cocrystals, ionic-cocrystals, and drug-drug salts/cocrystals have attracted much attention. The exploration of multicomponent crystals of pharmaceutical materials continues gaining interest in the pharmaceutical field due to the ability of crystals to modulate a broad range of physicochemical properties of the parent API, such as solubility, dissolution rate, stability, hygroscopicity, tabletability, permeability, and palatability. A crystal structure analysis plays an important role in addressing the key information in rationalizing the change in the physicochemical properties of multicomponent crystals.

This Special Issue on the “Crystal Structure and Properties of Multicomponent Pharmaceutical Materials” aims to highlight theoretical and experimental approaches to screening, structural analyses, physicochemical properties characterization, rationalization structure-property relationships, as well as the application of pharmaceutical multicomponent crystals. We encourage the submission of studies on new crystal structures and a characterization of the physicochemical properties of salts, cocrystals, hydrates/solvates, and their interdisciplinary forms of pharmaceutical multicomponent materials.

Contributions from both the industry and academia are welcome.

Dr. Hidehiro Uekusa
Dr. Yuda Prasetya Nugraha
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Crystals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.