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Computers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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AI in Bioinformatics

edited by

Mateo Sokač

submission deadline 31 Dec 2026 | 6 articles | Viewed by 4878 | Submission Open

Keywords: artificial intelligence; AI; bioinformatics; computational biology; machine learning

(This special issue belongs to the Section AI-Driven Innovations)

Intelligent Computing and Sensing Systems for Sustainable Precision Agriculture

edited by

Abhilash Chandel

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4617 | Submission Open

Keywords: sustainable precision agriculture; intelligent computing; sensing systems; smart farming; digital agriculture; artificial intelligence (AI); machine learning; Internet of Things (IoT); remote sensing; edge computing; cloud computing; robotics and automation; digital twins; data analytics; computer vision; wireless sensor networks; crop monitoring

(This special issue belongs to the Section AI-Driven Innovations)

Generative AI in Medicine: Emerging Applications, Challenges, and Future Directions

edited by Atsushi Teramoto

submission deadline 31 Dec 2026 | 3 articles | Viewed by 3665 | Submission Open

Keywords: generative AI; medical image synthesis; diffusion models; report generation; large language models (LLMs); clinical applications; deep learning; explainability; AI ethics in healthcare

(This special issue belongs to the Section AI-Driven Innovations)

Transformative Approaches in Education: Harnessing AI, Augmented Reality, and Virtual Reality for Innovative Teaching and Learning (2nd Edition)

edited by

Stamatios Papadakis

submission deadline 31 Dec 2026 | 3 articles | Viewed by 2522 | Submission Open

Keywords: artificial intelligence; augmented reality (AR); virtual reality (VR); immersive learning; educational technology; personalized learning; student engagement; 21st-century skills; curriculum design; technology integration; interactive learning environments; digital learning tools; transformative education; evidence-based practices; teacher training; innovative pedagogy; educational outcomes; cross-disciplinary approaches; learning experience design; gamification

(This special issue belongs to the Section Human–Computer Interactions)

Trustworthy and Efficient Large Language Models: Methods, Systems and Applications

edited by

Xueyi Li

Guangyao Zhang

and Yaoxiang Yu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1837 | Submission Open

Keywords: large language models (LLMs); trustworthiness; efficiency; interpretability; scalability; ethical AI; AI applications; optimization techniques; fault diagnosis; knowledge extraction

(This special issue belongs to the Section AI-Driven Innovations)

Advances in Computer Vision: Models, Learning, and Inference

edited by Abu Saleh Musa Miah,

Jungpil Shin

and Md. Al Mehedi Hasan

submission deadline 31 Dec 2026 | Viewed by 941 | Submission Open

Keywords: computer vision; visual recognition; deep learning for vision; generative models; 3D computer vision; geometric deep learning; video understanding; vision-language models; self-supervised learning; image synthesis; object detection and tracking; scene understanding; efficient inference; model compression; robustness and generalization; explainable AI (XAI) in vision

(This special issue belongs to the Section AI-Driven Innovations)

Cloud Computing and Big Data Mining—2nd Edition

edited by Rao Mikkilineni

submission deadline 31 Dec 2026 | 1 articles | Viewed by 926 | Submission Open

Keywords: cloud computing; big data mining; data analytics; machine learning; artificial intelligence; data security; data privacy; internet of things (IoT); edge computing; distributed computing; data warehousing; data processing; cloud storage; data visualization; hybrid cloud servers; edge cloud servers; integration of the internet of things

(This special issue belongs to the Section Cloud Continuum and Enabled Applications)

Intelligent Systems Security: AI-Driven Approaches for Attacks, Detection & Explainability

edited by

J. Gómez

submission deadline 31 Dec 2026 | 1 articles | Viewed by 871 | Submission Open

Keywords: systems security; AI-enhanced security methodologies; traditional security techniques; pentesting; intrusion detection systems (IDSs); zero-day threat detection; attack execution analysis; reverse engineering; explainable AI (XAI) for security; transparent security models; automated decision-making in cybersecurity; security lifecycle management; AI-driven threat detection; adversarial machine learning; human– AI collaboration in security; trustworthy AI Systems; real-time incident response

(This special issue belongs to the Section ICT Infrastructures for Cybersecurity)

AI/ML-Driven Intrusion Detection Systems for the Internet of Things: Techniques, Challenges, and Future Directions

edited by

Md Arafatur Rahman

and Prashant Pillai

submission deadline 31 Dec 2026 | Viewed by 420 | Submission Open

Keywords: IoT security; intrusion detection systems; AI-based intrusion detection; machine learning; anomaly detection; lightweight IDS; real-time monitoring; edge computing; big data analytics; explainable AI; scalable security solutions; threat detection

(This special issue belongs to the Section Internet of Things (IoT) and Industrial IoT)

Multimedia Data and Network Security: Emerging Trends and AI-Driven Threats and Defenses

edited by Zahid Akhtar

submission deadline 31 Dec 2026 | Viewed by 196 | Submission Open

Keywords: multimedia security; network security; data encryption; digital watermarking; steganography; content protection; cryptography; secure multimedia communication; secure multimedia streaming; multimedia forensics; network intrusion detection; secure data transmission and storage; multimedia authentication; secure multimedia storage; multimedia privacy; AI-driven cybersecurity; deepfake detection; privacy-preserving machine learning; secure cloud multimedia; IoT multimedia security; adversarial attacks on multimedia; blockchain for multimedia security; perceptual-based multimedia quality assessment; biometric security; secure video analytics

(This special issue belongs to the Section AI-Driven Innovations)

AI and Network Science for Biological Systems and Human Health

edited by

Ping Luo

submission deadline 31 Dec 2026 | 1 articles | Viewed by 177 | Submission Open

Keywords: artificial intelligence; network science; biological networks; network medicine; graph neural networks; multi-omics data integration; gene regulatory networks; protein– protein interaction networks; neural circuit analysis; disease module discovery; drug repurposing; precision medicine; personalized healthcare; infectious disease modeling; spreading dynamics; topological data analysis (TDA); explainable AI (XAI) in biomedicine; multi-modal learning in healthcare; patient stratification; biomarker discovery

(This special issue belongs to the Section AI-Driven Innovations)

The Internet of Things—Current Trends, Applications, and Future Challenges (3rd Edition)

edited by

Sergio Correia

and João Pedro Matos-Carvalho

submission deadline 31 Dec 2026 | Viewed by 98 | Submission Open

Keywords: internet of things (IoT); artificial intelligence and machine learning; blockchain; privacy and security; industry 4.0; cloud computing; big data; embedded computing; sensor networks; distributed computing; green computing and energy efficiency; internet of wearable things; healthcare; testbed and experimental results for the IoT; smart sensors; drones and UAVs; 5G and beyond-5G networks; software-defined wireless access networks; pervasive computing; social and environmental impacts

(This special issue belongs to the Section Internet of Things (IoT) and Industrial IoT)

From 5G to 6G: Emerging Technologies in Wireless Networks

edited by

Omar Younis Alani

submission deadline 31 Jan 2027 | Viewed by 169 | Submission Open

Keywords: 5G; 6G; wireless networks; terahertz communication; reconfigurable intelligent surfaces; massive MIMO; AI in networks; low-latency communications; energy-efficient networking; network security

(This special issue belongs to the Section Cloud Continuum and Enabled Applications)

Intelligence at the Edge: AI/ML for IoT Systems

edited by

Sanjoy Paul

submission deadline 31 Jan 2027 | Viewed by 125 | Submission Open

Keywords: edge intelligence for IoT; AI/ML at the network edge; lightweight intrusion detection; IoT security architectures; zero-day attack detection in edge networks; explainable AI (XAI) for edge systems; trustworthy edge AI; automated security response; adversarial machine learning for IoT; real-time threat mitigation; federated learning for edge security; resource-aware AI models; edge-based anomaly detection; privacy-preserving edge computing; human-in-the-loop edge security

(This special issue belongs to the Section AI-Driven Innovations)

The Digital Transformation of Education: Trends, Technologies, and Responsible Innovation

edited by Zoltán Szűts, Péter Ekler,

Kristóf Csorba

and

Bertalan Forstner

submission deadline 28 Feb 2027 | 3 articles | Viewed by 4120 | Submission Open

Keywords: computing education; software engineering education; artificial intelligence in education; large language models; intelligent tutoring systems; AR/VR/XR in education; innovative EdTech solutions; data privacy in EdTech; responsible educational technology; digital transformation in learning; adaptive learning technologies; gamification in computer science education; digital pedagogy

(This special issue belongs to the Section AI-Driven Innovations)

Intelligent Transportation Systems: Recent Advances

edited by

Teng Zhou

Zhizhe Lin

, Chunjie Cao and Youyi Song

submission deadline 31 Mar 2027 | Viewed by 130 | Submission Open

Keywords: smart city and urban mobility; autonomous vehicles and v2x communication; spatio-temporal big data analytics; edge intelligence and federated learning; traffic flow prediction and management

(This special issue belongs to the Section AI-Driven Innovations)

Future Trends in Computer Programming Education, 2nd Edition

edited by

Stelios Xinogalos

submission deadline 31 Mar 2027 | Viewed by 73 | Submission Open

Keywords: strategies for teaching programming (e.g.; object-first; imperative-first; function-first); programming languages for an introduction to programming; teaching approaches for an introduction to programming; procedural/object-oriented/web/game/etc. programming education; cultivating computational thinking skills through programming; educational programming environments; programming microworlds; structure editors; program/software visualization tools; software quality tools for education; tangible programming languages/environments; educational/serious games for programming; distributed pair programming

AI in Knowledge Management

edited by Murray Jennex

submission deadline 20 Apr 2027 | 2 articles | Viewed by 1090 | Submission Open

Keywords: knowledge creation; knowledge representation; knowledge discovery; artificial intelligence; knowledge management; knowledge retrieval; knowledge search; knowledge acquisition; machine learning with knowledge

(This special issue belongs to the Section AI-Driven Innovations)

Next-Generation Semantic Multimedia: Generative AI, Human-Centric Personalization, and Digital Sustainability

edited by

Phivos Mylonas

, Christos Troussas, Akrivi Krouska,

Manolis Wallace

and Maria Kouri

submission deadline 30 Apr 2027 | 1 articles | Viewed by 429 | Submission Open

Keywords: multimedia; contextual intelligence; sustainability; user profiling; AI; semantics

(This special issue belongs to the Section AI-Driven Innovations)

Advanced Software Engineering in the Age of Artificial Intelligence: Best Practices, Challenges, and Opportunities

edited by

Yan Liu

submission deadline 30 Apr 2027 | Viewed by 229 | Submission Open

Keywords: software engineering; AI4SE; SE4AI; explainable AI (XAI); distributed computing; cloud-native architecture; software quality; trustworthy systems; ethics in software development; lifecycle management

(This special issue belongs to the Section AI-Driven Innovations)

Advances in Explainable and Multimodal AI for Intelligent Systems and Medical Applications

edited by

Naeem Ullah

Javed Ali Khan

and

Muhammad Yaqoob

submission deadline 30 Apr 2027 | Viewed by 159 | Submission Open

Keywords: explainable artificial intelligence; multimodal learning; interpretable deep learning; intelligent systems; medical applications; data fusion; trustworthy AI; machine learning; computer vision; hybrid AI

(This special issue belongs to the Section AI-Driven Innovations)

Privacy-Preserving Computation and Secure Data Sharing in Modern Networks

edited by

Hui Cui

and Michael N. Johnstone

submission deadline 30 Apr 2027 | Viewed by 81 | Submission Open

Keywords: privacy-preserving computation; secure data sharing; secure multi-party computation; homomorphic encryption; federated learning; differential privacy; trusted execution environments; data anonymization; network security; distributed systems

(This special issue belongs to the Section ICT Infrastructures for Cybersecurity)

Explainable Artificial Intelligence for Signal Processing and Recognition

edited by

Andres Alvarez-Meza

submission deadline 20 May 2027 | Viewed by 554 | Submission Open

Keywords: trustworthy AI; explainable AI (XAI); biomedical signal processing; telecommunication signals; signal integrity; ethical AI; AI security; image processing; brain– computer interface; wireless health monitoring; deep learning; machine learning

(This special issue belongs to the Section AI-Driven Innovations)

AI in Action: Innovations and Breakthroughs

edited by

Xiaorui Shao

submission deadline 31 May 2027 | 5 articles | Viewed by 6150 | Submission Open

Keywords: artificial intelligence; generative AI; healthcare AI; explainable AI; AI for science

(This special issue belongs to the Section AI-Driven Innovations)

AI/ML-Driven EEG Signal Processing

edited by

Rui Zhang

and Peiyang Li

submission deadline 31 Oct 2027 | 1 articles | Viewed by 549 | Submission Open

Keywords: EEG signal processing; machine learning for EEG; deep learning; brain– computer interfaces; feature extraction; time-frequency analysis; EEG abnormalities detection; neurofeedback; big data in EEG; cognitive neuroscience

(This special issue belongs to the Section AI-Driven Innovations)

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