Advance on Transdermal Absorption in Children
A special issue of Children (ISSN 2227-9067).
Deadline for manuscript submissions: closed (5 June 2022) | Viewed by 303
Special Issue Editor
Special Issue Information
Dear Colleagues,
Transdermal is a route of administration wherein active ingredients are delivered across the skin for systemic distribution. Examples include transdermal patches used for medicine delivery. The drug is administered in the form of a patch or ointment that delivers the drug into the circulation for systemic effect. Transdermal administration offers a non-invasive and convenient method for pediatric drug delivery. The competent skin barrier function in term infants and older children limits both water loss and the percutaneous entry of chemicals including drugs, but the smaller doses required by children ease the attainment of therapeutic concentrations. Transdermal patches used in pediatrics include fentanyl, buprenorphine, clonidine, scopolamine, methylphenidate, estrogens, nicotine, and tulobuterol. In recent years, several approaches—for example, jet injectors, iontophoresis, microneedles, sonophoresis, and laser thermal ablation—have been employed for efficient transdermal delivery of small molecules, high molecular weight drugs, and vaccines in the pediatric population. We welcome the submission of original research papers, case reports, short communication, and literature/systematic reviews manifesting advancements in transdermal/transbuccosal drug delivery in children in the fields of formulation science, drug delivery (particularly transdermal, buccal, and mucosal).
Prof. Dr. Muhammad Sohail Arshad
Guest Editor
Manuscript Submission Information
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Keywords
- transdermal drug delivery
- transdermal patches
- pediatric dosage forms
- premature neonates
- iontophoresis
- skin
- stratum corneum
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