Obstetric Factors and Neonatal Outcomes: The Limit of Viability
A special issue of Children (ISSN 2227-9067).
Deadline for manuscript submissions: 5 October 2025 | Viewed by 1018

Special Issue Editors
Interests: obstetrics and gynecology; preeclampsia; intrauterine growth restriction
Special Issue Information
Dear Colleagues,
The most accepted definition of fetal viability is based on the gestational age and/or birth weight of a human fetus that is capable of surviving outside the uterus. The World Health Organization sets the viability at 22 weeks of gestation, or 500 g birth weight, or 25 cm of birth length. The variability between individuals has an important role. The inclusion of maternal risk factors, fetal anomalies, and emerging technologies, such as assisted reproduction techniques and preimplantation genetic testing, reflects current trends in practice and research. However, we need to focus on a clear central theme, such as improving outcomes in high-risk pregnancies. The fetal survival depends on the development of their organs. Improving the diagnostic methods, the proper monitoring of high-risk pregnancies with emphasis on clinical intervention demonstrates an improvement of maternal health and obstetrical outcomes. Peripartum management, such as a brief delay in delivery, proper monitoring of pre-eclampsia, proper management of the preterm premature rupturing of the membrane, or other high-risk pregnancies, may be beneficial for survival. We emphasize the importance of the limit of viability, with it being associated with a great burden of obstetrical and neonatal complications. In long-term follow-ups, many cases become a clinical challenge.
The aim of this Special Issue is to highlight how to increase fetal viability and diagnostic methods; we also focus on specific therapies to improve outcomes in high-risk pregnancies, aiming to enhance both fetal viability and maternal health. A multidisciplinary approach to this topic is essential to enhance newborn viability and improve obstetric and neonatal outcomes, incorporating personalized therapies and innovative diagnostic tools.
We are soliciting original articles, reviews, and case reports.
Dr. Melinda Ildiko Mitranovici
Dr. Lucian Puşcaşiu
Guest Editors
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Keywords
- neonatal limit of viability
- prematurity
- pre-eclampsia
- intrauterine growth restriction
- chorioamnionitis
- fetal anomalies
- diagnosis
- therapy
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