Retinoblastoma Disease and Eye Care in Children

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Ophthalmology".

Deadline for manuscript submissions: 5 December 2025 | Viewed by 31

Special Issue Editors


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Guest Editor
Department of Ophthalmology, Boston Children’s Hospital, Boston, MA 02115, USA
Interests: ophthalmology; genetics; strabismus; retinoblastoma; transcriptomics; protein interactions; chromatin conformation; embryonic stem cells; gene expression analysis

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Guest Editor
Research Informatics, Department of Information Technology, Boston Children’s Hospital, Boston, MA 02115, USA
Interests: ophthalmology; genetics; strabismus; retinoblastoma

Special Issue Information

Dear Colleagues,

Retinoblastoma is the most common intraocular malignant tumor in children, with an incidence of 1 in 15,000 to 1 in 20,000 live births. Survival rates for patients who are diagnosed early and treated promptly can exceed 95%. However, in low-income nations, the survival rate for retinoblastoma patients is approximately 50%, with the disease threatening not only their vision, but also their life.

Research has focused on genetics in order to improve the early detection, prognosis, and treatment of retinoblastoma by understanding its underlying molecular mechanisms.

In this Special Issue, we aim to publish research articles and reviews focused on the genetic pathways and genomic aspects of this disease, as well as those presenting advances in novel treatments and early detection and proposing future directions in this field of research. Submissions should explore potential biomarkers and molecular mechanisms that contribute to the progression of retinoblastoma and its prognosis or its resistance to current treatments.

Dr. Mayra Martinez Sanchez
Dr. Ashish Jain
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • retinoblastoma
  • biomarkers
  • treatment outcomes
  • novel therapeutic approaches
  • genomics
  • precision medicine
  • genetic testing

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Published Papers

This special issue is now open for submission.
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