Nanostructured Materials for Electrochemical Sensing

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Electrochemical Devices and Sensors".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 717

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Guest Editor
CIQUP/IMS, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, S/N, 4169-007 Porto, Portugal
Interests: electrochemistry; analytical chemistry; screen-printed electrodes (SPEs); electrochemical biosensors; amperometric; proteins
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Special Issue Information

Dear Colleagues,

Nanotechnology has revolutionized the field of electrochemical (bio)sensing, enhancing the capabilities and performance of devices significantly over recent decades. Currently, a diverse range of nanomaterials with various sizes, formats (e.g., thin films, spherical nanoparticles, and nanofibers), and compositions can be synthesized through well-established methodologies. These nanomaterials include the following:

(i) Carbon-based nanomaterials (e.g., carbon nanotubes (CNTs) and graphene oxide (GO)).

(ii) Noble metals and metal oxide NPs (e.g., Au, Ag, Cu, Pt, titanium dioxide, and zinc oxide).

(iii) Semiconductors materials (e.g., quantum dots (QDs)).

(iv) Hybrid composite nanomaterials.

These biocompatible nanostructures are highly appealing due to their exceptional surface area, mechanical strength, and electrocatalytic properties, which are particularly advantageous for the electroanalysis of biologically and chemically relevant (bio)molecules. Additionally, they can be integrated into biosensing platforms via straightforward adsorption or covalent immobilization techniques, ensuring stable and reproducible sensor fabrication. Alternatively, conducting surfaces can be modified with thin polymer films prepared through electrochemical polymerization. These films allow for fine-tuning of the metal–solution interface that can endow the sensor with specialized properties, such as antifouling, antibacterial, or self-cleaning capabilities. Furthermore, nanostructured materials may serve as a basis for the efficient coupling of affinity receptors, broadening their functional applications.

The practical applications of these high-performance electrochemical (bio)sensors are vast and varied, spanning environmental monitoring, food quality and safety assurance, precision agriculture, and advanced healthcare monitoring. These technologies are now being integrated into wearable, portable, and implantable bioanalytical systems, underscoring their relevance in modern-day innovations.

Dr. José Ribeiro
Guest Editor

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Keywords

  • nanomaterials
  • thin films
  • electrochemical biosensing
  • biosensors
  • sensors
  • immunosensors
  • genosensors
  • food
  • environment
  • disease biomarkers

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Published Papers (1 paper)

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19 pages, 3235 KiB  
Article
Electrochemical Detection of Bisphenol S Based on Molecularly Imprinted Polymers Grafted on Functionalized Multiwalled Carbon Nanotubes: A Facile Sensor Fabrication Approach
by Christopher Mwanza, Lin Zhao, Qing Zhang and Shou-Nian Ding
Chemosensors 2025, 13(7), 236; https://doi.org/10.3390/chemosensors13070236 - 30 Jun 2025
Viewed by 461
Abstract
Bisphenol S (BPS), a key ingredient in polycarbonate plastics and epoxy resins, is a known endocrine-disrupting compound that poses significant risks to human health and the environment. As such, the development of rapid and reliable analytical techniques for its detection is essential. In [...] Read more.
Bisphenol S (BPS), a key ingredient in polycarbonate plastics and epoxy resins, is a known endocrine-disrupting compound that poses significant risks to human health and the environment. As such, the development of rapid and reliable analytical techniques for its detection is essential. In this work, we present a newly engineered electrochemical sensor designed for the sensitive and selective detection of BPS using a straightforward and effective fabrication approach. The sensor was constructed by grafting molecularly imprinted polymers (MIPs) onto vinyl-functionalized multiwalled carbon nanotubes (f-MWCNTs). Ethylene glycol dimethacrylate and acrylamide were used as the cross-linker and functional monomer, respectively, in the synthesis of the MIP layer. The resulting MIP@f-MWCNT nanocomposite was characterized using Fourier-transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). The MIP@f-MWCNT material was then combined with chitosan, a biocompatible binder, to fabricate the final MIP@f-MWCNT/chitosan-modified glassy carbon electrode (GCE). Electrochemical evaluation showed a broad linear detection range from 1 to 60 µM (R2 = 0.992), with a sensitivity of 0.108 µA/µM and a detection limit of 2.00 µM. The sensor retained 96.0% of its response after four weeks and exhibited high selectivity against structural analogues. In spiked plastic extract samples, recoveries ranged from 95.6% to 105.0%. This robust, cost-effective, and scalable sensing platform holds strong potential for environmental monitoring, food safety applications, and real-time electrochemical detection of endocrine-disrupting compounds like BPS. Full article
(This article belongs to the Special Issue Nanostructured Materials for Electrochemical Sensing)
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